Evidence map›Paper›PMID 23390005›Full record

Trial reportDepression and anxiety2013

Benefits of child-focused anxiety treatments for parents and family functioning.

Courtney P Keeton, Golda S Ginsburg, Kelly L Drake, Dara Sakolsky, Philip C Kendall, Boris Birmaher, Anne Marie Albano, John S March, Moira Rynn, John Piacentini and 1 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Depression and anxiety, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Behavioral interventions for infant sleep problems: the role of parental cry tolerance and sleep-related cognitions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Trial
  6. Child Anxiety Prevention Study: Impact on Functional Outcomes.Child psychiatry and human development · 2017
    Trial
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  14. Group- versus Parent-Involvement CBT for Childhood Anxiety Disorders: Treatment Specificity and Long-term Recovery Mediation.Clinical psychological science : a journal of the Association for Psychological Science · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Courtney P KeetonDivision of Child and Adolescent Psychiatry, The Johns Hopkins University School of Medicine, 550 N. Broadway, Baltimore, MD 21205, USA. ckeeton@jhmi.edu
Golda S Ginsburg
Kelly L Drake
Dara Sakolsky
Philip C Kendall
Boris Birmaher
Anne Marie Albano
John S March
Moira Rynn
John Piacentini
John T Walkup
Columbia University Irving Medical Center · USJohns Hopkins Medicine · USCornell University · USDuke University Hospital · USJohns Hopkins University · USTemple University · USUniversity of California, Los Angeles · USUniversity of Pittsburgh · USUniversity of Pittsburgh Medical Center · US

Funding

Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064089 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GINSBURG, GOLDA SUSAN · 2002 to 2007
$3.1M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064003 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS · 2002 to 2007
$2.7M
Child/Adolescent Anxiety Multimodal Treatment Study (CAMS)U01MH064092 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ALBANO, ANNE MARIE · 2002 to 2007
$2.4M
Child and Adolescent Anxiety Multisite Study (CAMS)U01MH064107 · NIMH · DUKE UNIVERSITY · PI MARCH, JOHN S · 2002 to 2007
$2.4M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH063747 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI KENDALL, PHILIP C · 2002 to 2007
$2.2M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064088 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIACENTINI, JOHN C. · 2002 to 2007
$2.1M
3/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064089 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GINSBURG, GOLDA SUSAN, KEETON, COURTNEY PIERCE · 2010 to 2014
$925k
NIMH NIH HHS R01 MH064089NIMH NIH HHS U01 MH063747NIMH NIH HHS U01 MH064003NIMH NIH HHS U01 MH064088NIMH NIH HHS U01 MH064089NIMH NIH HHS U01 MH064092NIMH NIH HHS U01 MH064107
6 · The paper itself

Abstract

backgroundTo examine (1) changes in parent (global psychological distress, trait anxiety) and family (dysfunction, burden) functioning following 12 weeks of child-focused anxiety treatment, and (2) whether changes in these parent and family factors were associated with child's treatment condition and response.

methodsParticipants were 488 youth ages 7-17 years (50% female; mean age 10.7 years) who met DSM-IV-TR criteria for social phobia, separation anxiety, and/or generalized anxiety disorder, and their parents. Youth were randomly assigned to 12 weeks of "Coping Cat" individual cognitive-behavioral therapy (CBT), medication management with sertraline (SRT), their combination (COMB), or medication management with pill placebo (PBO) within the multisite Child/Adolescent Anxiety Multimodal Study (CAMS). At pre- and posttreatment, parents completed measures of trait anxiety, psychological distress, family functioning, and burden of child illness; children completed a measure of family functioning. Blinded independent evaluators rated child's response to treatment using the Clinical Global Impression-Improvement Scale at posttreatment.

resultsAnalyses of covariance revealed that parental psychological distress and trait anxiety, and parent-reported family dysfunction improved only for parents of children who were rated as treatment responders, and these changes were unrelated to treatment condition. Family burden and child-reported family dysfunction improved significantly from pre- to posttreatment regardless of treatment condition or response.

conclusionsFindings suggest that child-focused anxiety treatments, regardless of intervention condition, can result in improvements in nontargeted parent symptoms and family functioning particularly when children respond successfully to the treatment.

Indexed as

Family HealthAdolescentAnxiety DisordersAnxiety, SeparationChildCognitive Behavioral TherapyCombined Modality TherapyDouble-Blind MethodFemaleHumansMaleParentsPatient-Centered CarePhobic DisordersSelective Serotonin Reuptake InhibitorsSertralineSelective Serotonin Reuptake InhibitorsSertralinechild anxietycognitive-behavioral therapyfamily functioningfamily outcomesparent anxietyparent psychopathologypharmacotherapyrandomized controlled trialtreatment

Identifiers

PMID23390005
PMCPMC4144828
OpenAlexW2111960201

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.