ArticleMagnetic resonance in medicine2013
3D-mapping of phosphocreatine concentration in the human calf muscle at 7 T: comparison to 3 T.
Article in Magnetic resonance in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Fast 3DMagnetic resonance in medicine · 2025Article
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- Overview and progress of X-nuclei magnetic resonance imaging in biomedical studies.Magnetic resonance letters · 2023Review
- Compartment-based reconstruction of 3D acquisition-weightedNMR in biomedicine · 2023Article
- Phosphorus metabolism in the brain of cognitively normal midlife individuals at risk for Alzheimer's disease.Neuroimage. Reports · 2022Article
- 3DNMR in biomedicine · 2021Article
- ModularMagnetic resonance in medicine · 2019Article
- Dynamic phosphocreatine imaging with unlocalized pH assessment of the human lower leg muscle following exercise at 3T.Magnetic resonance in medicine · 2018Article
- In-vivoAnalytical biochemistry · 2017Review
- Bloch-Siegert B1+-mapping for human cardiac (31) P-MRS at 7 Tesla.Magnetic resonance in medicine · 2016Article
- Magnetic Resonance Imaging of Phosphocreatine and Determination of BOLD Kinetics in Lower Extremity Muscles using a Dual-Frequency Coil Array.Scientific reports · 2016Article
- A nested phosphorus and proton coil array for brain magnetic resonance imaging and spectroscopy.NeuroImage · 2016Article
- Three-dimensional saturation transfer ³¹P-MRI in muscles of the lower leg at 3.0 T.Scientific reports · 2014Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe development and implementation of a spectrally selective 3D-Turbo Spin Echo sequence for quantitative mapping of phosphocreatine (PCr) concentration in different muscles of the lower leg of healthy volunteers both at 3 T and 7 T.
methodsNine healthy volunteers were recruited, all of whom where scanned at 3 T and 7 T. Three dimensional PCr concentration maps were obtained after images were corrected for B1 inhomogeneities, T1 relaxation weighting, and partial volume of fatty tissue in the muscles. Two volunteers performed plantar flexions inside the magnet, and the oxidative capacity of their muscles was estimated.
resultsThree dimensional PCr concentration maps were obtained, with full muscle coverage and nominal voxel size of 0.52 mL at both fields. At 7 T a 2.7-fold increase of signal-to-noise ratio was achieved compared to 3 T.
conclusionImaging (31) P metabolites at 7 T allowed for significant increase in signal to noise ratio compared to imaging at 3 T, while quantification of the PCr concentration remained unaffected. The importance of such an increase in signal-to-noise ratio is 2-fold, first higher resolution images with reduced partial volume effects can be acquired, and second multiple measurements such as dynamic imaging of PCr post-exercise, (31) P magnetization transfer, or other (1) H measurements, can be acquired in a single imaging session.
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