ArticleCognitive, affective & behavioral neuroscience2013
Evidence for a detrimental relationship between hypertension history, prospective memory, and prefrontal cortex white matter in cognitively normal older adults.
Article in Cognitive, affective & behavioral neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The trial behind it
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Who cites it
8 citing papers in PubMed.
- Multifaceted Prospective Memory Intervention to Improve Medication Adherence.Journal of the American Geriatrics Society · 2016Trial
- Prospective memory impairment in neurological disorders: implications and management.Nature reviews. Neurology · 2021Review
- Hypertension is associated with reduced hippocampal connectivity and impaired memory.EBioMedicine · 2020Article
- Structural correlates of commission errors in prospective memory.Cortex; a journal devoted to the study of the nervous system and behavior · 2020Article
- User Insights for Design of an Antihypertensive Medication Management Application.Proceedings of the Human Factors and Ergonomics Society ... Annual Meeting. Human Factors and Ergonomics Society. Annual meeting · 2018Article
- Do Older Adults Need Sleep? A Review of Neuroimaging, Sleep, and Aging Studies.Current sleep medicine reports · 2017Article
- An implementation intention strategy can improve prospective memory in older adults with very mild Alzheimer's disease.The British journal of clinical psychology · 2016Article
- Prospective memory and aging: evidence for preserved spontaneous retrieval with exact but not related cues.Psychology and aging · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Hypertension affects many older adults and is associated with impaired neural and cognitive functioning. We investigated whether a history of hypertension was associated with impairments to prospective memory, which refers to the ability to remember to perform delayed intentions, such as remembering to take medication. Thirty-two cognitively normal older adult participants with or without a history of hypertension (self-reported) performed two laboratory prospective memory tasks, one that relied more strongly on executive control (nonfocal prospective memory) and one that relied more strongly on spontaneous memory retrieval processes (focal prospective memory). We observed hypertension-related impairments for nonfocal, but not focal, prospective memory. To complement our behavioral approach, we conducted a retrospective analysis of available structural magnetic resonance imaging data. Lower white matter volume estimates in the anterior prefrontal cortex were associated with lower nonfocal prospective memory and with a history of hypertension. A history of hypertension may be associated with worsened executive control and lower prefrontal white matter volume. The translational implication is that individuals who must remember to take antihypertensive medications and to monitor their blood pressure at home may be impaired in the executive control process that helps to support these prospective memory behaviors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.