Evidence map›Paper›PMID 23389040›Full record

ArticleInternational journal of molecular sciences2013

Natural products as a source for treating neglected parasitic diseases.

Dieudonné Ndjonka, Ludmila Nakamura Rapado, Ariel M Silber, Eva Liebau, Carsten Wrenger

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 150 citations in OpenAlex.

  1. Article
  2. Review
  3. Biological activity ofHelminthologia · 2026
    Article
  4. Article
  5. Anthelmintic activity of crude and separated extract ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  6. Article
  7. An Inventory of Anthelmintic Plants across the Globe.Pathogens (Basel, Switzerland) · 2023
    Review
  8. Apigenin is a promising molecule for treatment of visceral leishmaniasis.Frontiers in cellular and infection microbiology · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cytotoxicity of Essential OilMolecules (Basel, Switzerland) · 2021
    Article
  17. Review
  18. Epigallocathechin-Frontiers in cellular and infection microbiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dieudonné NdjonkaDepartment of Biological Sciences, Faculty of Science, University of Ngaoundere, B. P. 454, Cameroon. liebaue@uni-muenster.de.
Ludmila Nakamura Rapado
Ariel M Silber
Eva Liebau
Carsten Wrenger
Universidade de São Paulo · BRUniversity of Ngaoundéré · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases caused by parasites are a major threat for the entire mankind, especially in the tropics. More than 1 billion people world-wide are directly exposed to tropical parasites such as the causative agents of trypanosomiasis, leishmaniasis, schistosomiasis, lymphatic filariasis and onchocerciasis, which represent a major health problem, particularly in impecunious areas. Unlike most antibiotics, there is no "general" antiparasitic drug available. Here, the selection of antiparasitic drugs varies between different organisms. Some of the currently available drugs are chemically de novo synthesized, however, the majority of drugs are derived from natural sources such as plants which have subsequently been chemically modified to warrant higher potency against these human pathogens. In this review article we will provide an overview of the current status of plant derived pharmaceuticals and their chemical modifications to target parasite-specific peculiarities in order to interfere with their proliferation in the human host.

Identifiers

PMID23389040
PMCPMC3588050
OpenAlexW2053926001

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.