ReviewNature reviews. Cancer2013
Tracking cells in their native habitat: lineage tracing in epithelial neoplasia.
Review in Nature reviews. Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 57 citations in OpenAlex.
- Engineering Protein Stability with Small Molecules: A Review of the ecDHFR Destabilizing Domain System.ACS chemical biology · 2026Review
- Hotspots and frontiers of the relationship between hepatocellular carcinoma and cancer-associated fibroblasts: a bibliometric analysis and review.Discover oncology · 2025Article
- Lifting regenerative barriers promotes epithelial cell fate plasticity supporting lineage conversion.Nature communications · 2025Article
- Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin.The Journal of investigative dermatology · 2024Review
- The role of microRNAs in the modulation of cancer-associated fibroblasts activity during pancreatic cancer pathogenesis.Journal of physiology and biochemistry · 2023Review
- Signaling pathways in cancer-associated fibroblasts: recent advances and future perspectives.Cancer communications (London, England) · 2023Review
- Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives.Molecular cancer · 2021Review
- A biomechanical switch regulates the transition towards homeostasis in oesophageal epithelium.Nature cell biology · 2021Article
- The Interaction Between Long Non-Coding RNAs and Cancer-Associated Fibroblasts in Lung Cancer.Frontiers in cell and developmental biology · 2021Review
- The promising role of noncoding RNAs in cancer-associated fibroblasts: an overview of current status and future perspectives.Journal of hematology & oncology · 2020Review
- Genetic lineage tracing with multiple DNA recombinases: A user's guide for conducting more precise cell fate mapping studies.The Journal of biological chemistry · 2020Review
- Radiation-induced tissue damage and response.The Journal of pathology · 2020Review
- A single-progenitor model as the unifying paradigm of epidermal and esophageal epithelial maintenance in mice.Nature communications · 2020Article
- A framework for advancing our understanding of cancer-associated fibroblasts.Nature reviews. Cancer · 2020Review
- Outcompeting p53-Mutant Cells in the Normal Esophagus by Redox Manipulation.Cell stem cell · 2019Article
- Prostate Stem Cells and Cancer Stem Cells.Cold Spring Harbor perspectives in medicine · 2019Review
- Lineage Plasticity in Cancer Progression and Treatment.Annual review of cancer biology · 2018Article
- Imaging to study solid tumour origin and progression: lessons from research and clinical oncology.Immunology and cell biology · 2017Review
- GLI1Molecular and cellular endocrinology · 2017Article
- Oesophageal Stem Cells and Cancer.Advances in experimental medicine and biology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
For tumours to develop, mutations must disrupt tissue homeostasis in favour of deregulated proliferation. Genetic lineage tracing has uncovered the behaviour of proliferating cells that underpins the maintenance of epithelial tissues and the barriers that are broken in neoplastic transformation. In this Review, we focus on new insights revealed by quantifying the behaviour of normal, preneoplastic and tumour cells in epithelia in transgenic mice and consider their potential importance in humans.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.