ArticleBiology of mood & anxiety disorders2013
Therapygenetics: Using genetic markers to predict response to psychological treatment for mood and anxiety disorders.
Article in Biology of mood & anxiety disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Polygenic Risk for Major Depression Interacts with Parental Criticism in Predicting Adolescent Depressive Symptom Development.Journal of youth and adolescence · 2021Pooled it
- A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders.Translational psychiatry · 2019Pooled it
- Theranostic markers for personalized therapy of spider phobia: Methods of a bicentric external cross-validation machine learning approach.International journal of methods in psychiatric research · 2020Trial
- Genome-wide association study of response to cognitive-behavioural therapy in children with anxiety disorders.The British journal of psychiatry : the journal of mental science · 2016Trial
- Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders.The British journal of psychiatry : the journal of mental science · 2016Trial
- The functional -1019C/G HTR1A polymorphism and mechanisms of fear.Translational psychiatry · 2014Trial
- Therapygenetics in mindfulness-based cognitive therapy: do genes have an impact on therapy-induced change in real-life positive affective experiences?Translational psychiatry · 2014Trial
- Prediction of Clinically Meaningful Improvement After Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety Disorders: Machine Learning-Based Predictive Model Development and Temporal Validation Study.Journal of medical Internet research · 2026Article
- Association Between Polygenic Risk and Symptom Severity Change After Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2025Article
- Polygenic scores and symptom severity change after internet-delivered cognitive behaviour therapy for depression and anxiety.Discover mental health · 2025Article
- Research Review: A review of the past decade of family and genomic studies on adolescent mental health.Journal of child psychology and psychiatry, and allied disciplines · 2025Review
- Transcriptomics and psychotherapy: An integrative review.Brain, behavior, & immunity - health · 2024Review
- Are There Biological Correlates of Response to Yoga-Based Interventions in Depression? A Critical Scoping Review.Brain sciences · 2024Article
- Psychotherapies and digital interventions for OCD in adults: What do we know, what do we need still to explore?Comprehensive psychiatry · 2023Review
- Genetics of obsessive-compulsive disorder.Psychological medicine · 2021Review
- Genetic Predictors of Response to Acupuncture or Cognitive Behavioral Therapy for Insomnia in Cancer Survivors: An Exploratory Analysis.Journal of pain and symptom management · 2021Article
- A bioinformatic study revealed serotonergic neurons are involved in the etiology and therapygenetics of anxiety disorders.Translational psychiatry · 2021Article
- An Update on Precision Medicine Advances In Neurodevelopmental Disorders.Psychiatric annals · 2021Article
- Integrative DNA Methylation and Gene Expression Analysis of Cognitive Behavioral Therapy Response in Children and Adolescents with Obsessive-Compulsive Disorder; a Pilot Study.Pharmacogenomics and personalized medicine · 2021Article
- Considerations for Pairing Cognitive Behavioral Therapies and Non-invasive Brain Stimulation: Ignore at Your Own Risk.Frontiers in psychiatry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Considerable variation is evident in response to psychological therapies for mood and anxiety disorders. Genetic factors alongside environmental variables and gene-environment interactions are implicated in the etiology of these disorders and it is plausible that these same factors may also be important in predicting individual differences in response to psychological treatment. In this article, we review the evidence that genetic variation influences psychological treatment outcomes with a primary focus on mood and anxiety disorders. Unlike most past work, which has considered prediction of response to pharmacotherapy, this article reviews recent work in the field of therapygenetics, namely the role of genes in predicting psychological treatment response. As this is a field in its infancy, methodological recommendations are made and opportunities for future research are identified.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.