ArticleInternational journal of pediatric endocrinology2013
Factors associated with low bone density in patients referred for assessment of bone health.
Article in International journal of pediatric endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Bone mineral density in adolescents and young women with hypogonadism: a DXA-based comparative analysis.Journal of the Turkish German Gynecological Association · 2026Article
- The Regulation of Marrow Fat by Vitamin D: Molecular Mechanisms and Clinical Implications.Current osteoporosis reports · 2019Review
- Article
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Authors and funding
4 authors.
Funding
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Abstract
backgroundTo identify factors that predict low bone mineral density (BMD) in pediatric patients referred for dual-energy x-ray absorptiometry assessments.
methodsThis is a retrospective cohort study of 304 children and adolescents referred for dual-energy x-ray absorptiometry assessments at a tertiary care center. Outcomes included risk factors which predicted a significant low bone density for age, defined as BMD Z-score ≤ -2.0 SD. A univariate analysis involved Chi-square, Fisher's Exact test, and analysis of variance, and multivariate logistic regression models were constructed to determine predictors of low bone mineral density.
resultsIn the multivariate logistic regression model, predictors of low bone mineral density included low body mass index Z-score (odds ratio 0.52, 95% confidence interval 0.39 - 0.69), low height Z-score (OR 0.71, 95% CI 0.57 - 0.88), vitamin D insufficiency (OR 3.97, 95% CI 2.08 - 7.59), and history of bone marrow transplant (OR 5.78, 95% CI 1.00 - 33.45).
conclusionsUnderlying health problems and associated treatments can impair bone mineral accrual. We identified risk factors most predictive of low bone mineral density in subjects referred for bone density measurement. Recognition of these factors may allow for earlier assessment to maximize bone mass in at-risk children.
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