Evidence map›Paper›PMID 23387510›Full record

ArticleJournal of clinical and experimental neuropsychology2013

Association between cerebral metabolism and Rey-Osterrieth Complex Figure Test performance in Alzheimer's disease.

Rebecca J Melrose, Dylan Harwood, Theresa Khoo, Mark Mandelkern, David L Sultzer

Abstract read
In one paragraph

Article in Journal of clinical and experimental neuropsychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. BrainEuropean journal of nuclear medicine and molecular imaging · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rebecca J MelroseBrain, Behavior & Aging Research Center, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA. rjmelrose@ucla.edu
Dylan Harwood
Theresa Khoo
Mark Mandelkern
David L Sultzer

Funding

Visual Processing and Later Cognitive Effects in Infants with fragile X SyndromeR01HD056031 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RIVERA, SUSAN M · 2007 to 2011
$1.2M
DELUSIONS AND CEREBRAL METABOLISM IN ALZHEIMERS DISEASER01MH056031 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SULTZER, DAVID · 1997 to 2001
$412k
NICHD NIH HHS R01 HD056031NIMH NIH HHS R01 MH056031NIMH NIH HHS R01 MH56031
6 · The paper itself

Abstract

The copy condition of the Rey-Osterrieth Complex Figure (ROCF) is sensitive to Alzheimer's disease (AD) pathology, but its neural correlates remain unclear. We used fluorodeoxyglucose positron emission tomography (FDG-PET) to elucidate this association in 77 patients with probable AD. We observed a correlation between ROCF and metabolic rate of bilateral temporal-parietal cortex and occipital lobe, and right frontal lobe. Global and local elements of the ROCF correlated with metabolic rate of these same regions. The copy approach correlated with right lateral temporal cortex. The ROCF appears reflective of posterior temporal-parietal cortex functioning, highlighting the role of visuospatial processing in constructional abilities in AD.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseBrainBrain MappingFemaleFunctional NeuroimagingHumansImage Processing, Computer-AssistedMaleMiddle AgedNeuropsychological TestsRadionuclide Imaging

Identifiers

PMID23387510
PMCPMC3727972

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.