Evidence map›Paper›PMID 23387482›Full record

ReviewBiomarkers in medicine2013

Immunotherapeutic strategies to target prognostic and predictive markers of cancer.

Michael S Magee, Adam E Snook, Glen P Marszalowicz, Scott A Waldman

Abstract readReview
In one paragraph

Review in Biomarkers in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Therapeutic Applications for Oncolytic Self-Replicating RNA Viruses.International journal of molecular sciences · 2022
    Review
  2. Alphaviruses in Cancer Therapy.Frontiers in molecular biosciences · 2022
    Review
  3. Cancer and orofacial pain.Medicina oral, patologia oral y cirugia bucal · 2016
    Review
  4. Cancer and Referred Facial Pain.Current pain and headache reports · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael S MageeDepartment of Pharmacology & Experimental Therapeutics, Thomas Jefferson University, Philadelphia, 132 South 10th Street, 1170 Main, Philadelphia, PA 19107, USA.
Adam E Snook
Glen P Marszalowicz
Scott A Waldman

Funding

X-Ray Crystallography and Macromolecular CharacterizationP30CA056036 · NCI · THOMAS JEFFERSON UNIVERSITY · PI Felix Jinhyun Kim · 1995 to 2026
$94.8M
GUCY2C hormone signaling at the intersection of obesity and colorectal cancer(PQ1R01CA170533 · NCI · THOMAS JEFFERSON UNIVERSITY · PI WALDMAN, SCOTT A · 2012 to 2015
$1.3M
Occult lymph node metastases and racial disparities in colon cancer outcomesRC1CA146033 · NCI · THOMAS JEFFERSON UNIVERSITY · PI WALDMAN, SCOTT A · 2009 to 2010
$997k
GUCY2C targeted adoptive T cell therapy to treat metastatic colorectal cancerF31CA171672 · NCI · THOMAS JEFFERSON UNIVERSITY · PI MAGEE, MICHAEL S. · 2012 to 2013
$84k
NCI NIH HHS CA146033NCI NIH HHS CA170533NCI NIH HHS F31 CA171672NCI NIH HHS F31CA171672NCI NIH HHS P30 CA056036NCI NIH HHS R01 CA170533NCI NIH HHS RC1 CA146033
6 · The paper itself

Abstract

Throughout the last century medical advances in cancer treatment in the fields of surgery, radiation therapy and chemotherapy have greatly impacted patients' survival rates. Nevertheless, cancer remains a significant cause of mortality, with an estimated 7.6 million deaths worldwide in 2008, reflecting the inability of existing therapies to effectively cure disease. The emergence of vaccines and their successes in preventing the spread of infectious diseases has demonstrated the unique specificity and therapeutic potential of the immune system. This potential has driven the development of novel cancer immunotherapeutics. This review focuses on the current status of the use of immunologic effectors to target known biomarkers in cancer.

Indexed as

ImmunotherapyAntibodies, MonoclonalBiomarkersCancer VaccinesCell- and Tissue-Based TherapyHumansImmunotoxinsNeoplasmsPrognosisT-LymphocytesAntibodies, MonoclonalBiomarkersCancer VaccinesImmunotoxins

Identifiers

PMID23387482
PMCPMC3755011

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.