ArticleJournal of experimental botany2013
Structure-function analysis of the GmRIC1 signal peptide and CLE domain required for nodulation control in soybean.
Article in Journal of experimental botany, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Article
- A Comprehensive Transcriptome Atlas Reveals the Crucial Role of LncRNAs in Maintaining Nodulation Homeostasis in Soybean.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- CLAVATA signaling in plant-environment interactions.Plant physiology · 2024Review
- Progress in soybean functional genomics over the past decade.Plant biotechnology journal · 2022Review
- Systemic Optimization of Legume Nodulation: A Shoot-Derived Regulator, miR2111.Frontiers in plant science · 2021Review
- MIR2111-5 locus and shoot-accumulated mature miR2111 systemically enhance nodulation depending on HAR1 in Lotus japonicus.Nature communications · 2020Article
- Redox Systemic Signaling and Induced Tolerance Responses During Soybean-Frontiers in plant science · 2019Article
- A NIN-LIKE PROTEIN mediates nitrate-induced control of root nodule symbiosis in Lotus japonicus.Nature communications · 2018Article
- The Soybean GmNARK Affects ABA and Salt Responses in TransgenicFrontiers in plant science · 2018Article
- CLE peptide-encoding gene families in Medicago truncatula and Lotus japonicus, compared with those of soybean, common bean and Arabidopsis.Scientific reports · 2017Article
- Differential CLE peptide perception by plant receptors implicated from structural and functional analyses of TDIF-TDR interactions.PloS one · 2017Article
- Expression of the CLE-RS3 gene suppresses root nodulation in Lotus japonicus.Journal of plant research · 2016Article
- Genome-wide annotation and characterization of CLAVATA/ESR (CLE) peptide hormones of soybean (Glycine max) and common bean (Phaseolus vulgaris), and their orthologues of Arabidopsis thaliana.Journal of experimental botany · 2015Article
- Antagonistic peptide technology for functional dissection of CLE peptides revisited.Journal of experimental botany · 2015Article
- Dynamics of long-distance signaling via plant vascular tissues.Frontiers in plant science · 2015Review
- Secretion systems and signal exchange between nitrogen-fixing rhizobia and legumes.Frontiers in plant science · 2015Review
- Phytohormone regulation of legume-rhizobia interactions.Journal of chemical ecology · 2014Review
- The potential roles of strigolactones and brassinosteroids in the autoregulation of nodulation pathway.Annals of botany · 2014Article
- Effect of nitrate on nodule and root growth of soybean (Glycine max (L.) Merr.).International journal of molecular sciences · 2014Article
- Spatial expression of CLAVATA3 in the shoot apical meristem suggests it is not a stem cell marker in soybean.Journal of experimental botany · 2013Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Legumes control the nitrogen-fixing root nodule symbiosis in response to external and internal stimuli, such as nitrate, and via systemic autoregulation of nodulation (AON). Overexpression of the CLV3/ESR-related (CLE) pre-propeptide-encoding genes GmNIC1 (nitrate-induced and acting locally) and GmRIC1 (Bradyrhizobium-induced and acting systemically) suppresses soybean nodulation dependent on the activity of the nodulation autoregulation receptor kinase (GmNARK). This nodule inhibition response was used to assess the relative importance of key structural components within and around the CLE domain sequences of these genes. Using a site-directed mutagenesis approach, mutants were produced at each amino acid within the CLE domain (RLAPEGPDPHHN) of GmRIC1. This approach identified the Arg1, Ala3, Pro4, Gly6, Pro7, Asp8, His11, and Asn12 residues as critical to GmRIC1 nodulation suppression activity (NSA). In contrast, none of the mutations in conserved residues outside of the CLE domain showed compromised NSA. Chimeric genes derived from combinations of GmRIC1 and GmNIC1 domains were used to determine the role of each pre-propeptide domain in NSA differences that exist between the two peptides. It was found that the transit peptide and CLE peptide regions of GmRIC1 significantly enhanced activity of GmNIC1. In contrast, the comparable GmNIC1 domains reduced the NSA of GmRIC1. Identification of these critical residues and domains provides a better understanding of how these hormone-like peptides function in plant development and regulation.
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