Evidence map›Paper›PMID 23385869›Full record

ReviewNature reviews. Neuroscience2013

New insights into the classification and nomenclature of cortical GABAergic interneurons.

Javier DeFelipe, Pedro L López-Cruz, Ruth Benavides-Piccione, Concha Bielza, Pedro Larrañaga, Stewart Anderson, Andreas Burkhalter, Bruno Cauli, Alfonso Fairén, Dirk Feldmeyer and 32 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 482 papers.

0numbers the graph read from it
0cells of the map it votes in
482citing papers in PubMed
111.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

482 citing papers in PubMed, 852 citations in OpenAlex.

  1. Article
  2. Article
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  4. Pathophysiology and Prognostic Significance of Myoclonus in Hypoxic-Ischemic Encephalopathy.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2026
    Review
  5. Article
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  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. The grand challenge in cellular neurophysiology.Frontiers in cellular neuroscience · 2026
    Article
  13. A neuron type-specific microexon inbioRxiv : the preprint server for biology · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

422 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 9 countries.

Javier DeFelipeLaboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Campus Montegancedo S/N, Pozuelo de Alarcón, 28223 Madrid, Spain. defelipe@cajal.csic.es
Pedro L López-Cruz
Ruth Benavides-Piccione
Concha Bielza
Pedro Larrañaga
Stewart Anderson
Andreas Burkhalter
Bruno Cauli
Alfonso Fairén
Dirk Feldmeyer
Gord Fishell
David Fitzpatrick
Tamás F Freund
Guillermo González-Burgos
Shaul Hestrin
Sean Hill
Patrick R Hof
Josh Huang
Edward G Jones
Yasuo Kawaguchi
Zoltán Kisvárday
Yoshiyuki Kubota
David A Lewis
Oscar Marín
Henry Markram
Chris J McBain
Hanno S Meyer
Hannah Monyer
Sacha B Nelson
Kathleen Rockland
Jean Rossier
John L R Rubenstein
Bernardo Rudy
Massimo Scanziani
Gordon M Shepherd
Chet C Sherwood
Jochen F Staiger
Gábor Tamás
Alex Thomson
Yun Wang
Rafael Yuste
Giorgio A Ascoli
Universidad Politécnica de Madrid · ESÉcole Polytechnique Fédérale de Lausanne · CHInstituto de Neurociencias · ESNational Institute for Physiological Sciences · JPUniversity of Pittsburgh · USBoston University · USBrandeis University · USCentre Hospitalier Sainte-Anne · FRCentre National de la Recherche Scientifique · FRChildren's Hospital of Philadelphia · USCold Spring Harbor Laboratory · USColumbia University · USEunice Kennedy Shriver National Institute of Child Health and Human Development · USGeorge Mason University · USGeorge Washington University · USHoward Hughes Medical Institute · USHUN-REN Institute of Experimental Medicine · HUIcahn School of Medicine at Mount Sinai · USInstituto Cajal · ESMax Planck Florida Institute for Neuroscience · US

Funding

Cellular And Synaptic Physiology Of Hippocampal InterneuronsZIAHD001205 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MCBAIN, CHRIS J. · 2009 to 2025
$45.8M
Research BaseP30DK063720 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUMMEL, MATTHEW F · 2003 to 2019
$21.8M
SENSELAB: INTEGRATION OF MULTIDISCIPLINARY SENSORY DATAP01DC004732 · NIDCD · YALE UNIVERSITY · PI SHEPHERD, GORDON · 2000 to 2008
$10.2M
SCHIZOPHRENIA AND CORTICAL DOPAMINE/GABA INTERACTIONSR01MH043784 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LEWIS, DAVID A · 1988 to 2023
$7.2M
Generation and Description of Neuronal Morphology and ConnectivityR01NS039600 · NINDS · GEORGE MASON UNIVERSITY · PI ASCOLI, GIORGIO A · 1999 to 2024
$6.9M
SenseLab: Integration of Multidisciplinary Sensory DataR01DC009977 · NIDCD · YALE UNIVERSITY · PI HINES, MICHAEL L, MCDOUGAL, ROBERT A. · 2009 to 2018
$6.7M
IMAGING FUNCTIONAL CONNECTIVITY IN VISUAL CORTEXR01EY011787 · NEI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI YUSTE, RAFAEL · 1998 to 2021
$6.4M
EXPRESSION AND FUNCTION OF K+ CHANNEL GENES IN THE CNSR01NS030989 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RUDY, BERNARDO · 1992 to 2015
$6.3M
Synaptic Action in the Visual CortexR01EY012114 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI HESTRIN, SHAUL · 1998 to 2013
$4.2M
A Database of Mammalian Neuronal Cell TypesR01NS075007 · NINDS · BRANDEIS UNIVERSITY · PI NELSON, SACHA B · 2012 to 2016
$1.8M
NEI NIH HHS R01 EY011787NEI NIH HHS R01 EY012114NIDCD NIH HHS P01 DC004732NIDCD NIH HHS R01 DC009977NIDDK NIH HHS P30 DK063720NIMH NIH HHS R01 MH043784NINDS NIH HHS R01 NS030989NINDS NIH HHS R01 NS039600NINDS NIH HHS R01 NS075007PHS HHS R01-39600
6 · The paper itself

Abstract

A systematic classification and accepted nomenclature of neuron types is much needed but is currently lacking. This article describes a possible taxonomical solution for classifying GABAergic interneurons of the cerebral cortex based on a novel, web-based interactive system that allows experts to classify neurons with pre-determined criteria. Using Bayesian analysis and clustering algorithms on the resulting data, we investigated the suitability of several anatomical terms and neuron names for cortical GABAergic interneurons. Moreover, we show that supervised classification models could automatically categorize interneurons in agreement with experts' assignments. These results demonstrate a practical and objective approach to the naming, characterization and classification of neurons based on community consensus.

Indexed as

AlgorithmsTerminology as TopicAnimalsBayes TheoremCerebral CortexCluster Analysisgamma-Aminobutyric AcidHumansInterneuronsgamma-Aminobutyric Acid

Identifiers

PMID23385869
PMCPMC3619199
OpenAlexW1995031373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.