Evidence map›Paper›PMID 23385724›Full record

ReviewNature reviews. Molecular cell biology2013

Charity begins at home: non-coding RNA functions in DNA repair.

Dipanjan Chowdhury, Young Eun Choi, Marie Eve Brault

Abstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
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  4. NEAT1 promotes genome stability via mGenes & development · 2024
    Article
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  14. Frontiers in molecular biosciences · 2022
    Article
  15. Review
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  19. Review
  20. Review

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dipanjan ChowdhuryDivision of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA. dipanjan_chowdhury@dfci.harvard.edu
Young Eun Choi
Marie Eve Brault

Funding

Molecular mechanism and relevance of microRNAs in DSB repair pathway choiceR01CA142698 · NCI · DANA-FARBER CANCER INST · PI CHOWDHURY, DIPANJAN · 2010 to 2019
$3.8M
Serum microRNA as biomarker for radiation injury to lung and hematopoietic cellsR01AI101897 · NIAID · DANA-FARBER CANCER INST · PI CHOWDHURY, DIPANJAN · 2012 to 2016
$2.1M
NCI NIH HHS R01 CA142698NCI NIH HHS R01CA142698NIAID NIH HHS R01 AI101897NIAID NIH HHS R01 AI101897‑01
6 · The paper itself

Abstract

During the past decade, evolutionarily conserved microRNAs (miRNAs) have been characterized as regulators of almost every cellular process and signalling pathway. There is now emerging evidence that this new class of regulators also impinges on the DNA damage response (DDR). Both miRNAs and other small non-coding RNAs (ncRNAs) are induced at DNA breaks and mediate the repair process. These intriguing observations raise the possibility that crosstalk between ncRNAs and the DDR might provide a means of efficient and accurate DNA repair and facilitate the maintenance of genomic stability.

Indexed as

DNA BreaksDNA RepairCell CycleCell Physiological PhenomenaMicroRNAsRNA, UntranslatedSignal TransductionMicroRNAsRNA, Untranslated

Identifiers

PMID23385724
PMCPMC3904369

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.