ArticleNature communications2013
Developmental evidence for serial homology of the vertebrate jaw and gill arch skeleton.
Article in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 79 citations in OpenAlex.
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- Rhythmic chew cycles with distinct fast and slow phases are ancestral to gnathostomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- The genetics-morphology-behavior trifecta: Unraveling the single greatest limitation affecting our understanding of chondrichthyan evolution.Ecology and evolution · 2023Article
- The pseudobranch of jawed vertebrates is a mandibular arch-derived gill.Development (Cambridge, England) · 2022Article
- Pupil dilation and constriction in the skate Leucoraja erinacea in a simulated natural light field.The Journal of experimental biology · 2022Article
- Conserved and unique transcriptional features of pharyngeal arches in the skate (Leucoraja erinacea) and evolution of the jaw.Molecular biology and evolution · 2021Article
- Gene coexpression networks reveal molecular interactions underlying cichlid jaw modularity.BMC ecology and evolution · 2021Article
- New Species Can Broaden Myelin Research: Suitability of Little Skate,Life (Basel, Switzerland) · 2021Article
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- Evolution of vertebrate gill covers via shifts in an ancient Pou3f3 enhancer.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
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- Evolution of the Chordate Telencephalon.Current biology : CB · 2019Review
- Evolvability of the vertebrate craniofacial skeleton.Seminars in cell & developmental biology · 2019Review
- The pharynx of the stem-chondrichthyan Ptomacanthus and the early evolution of the gnathostome gill skeleton.Nature communications · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 3 countries.
Funding
Abstract
Gegenbaur's classical hypothesis of jaw-gill arch serial homology is widely cited, but remains unsupported by either palaeontological evidence (for example, a series of fossils reflecting the stepwise transformation of a gill arch into a jaw) or developmental genetic data (for example, shared molecular mechanisms underlying segment identity in the mandibular, hyoid and gill arch endoskeletons). Here we show that nested expression of Dlx genes--the 'Dlx code' that specifies upper and lower jaw identity in mammals and teleosts--is a primitive feature of the mandibular, hyoid and gill arches of jawed vertebrates. Using fate-mapping techniques, we demonstrate that the principal dorsal and ventral endoskeletal segments of the jaw, hyoid and gill arches of the skate Leucoraja erinacea derive from molecularly equivalent mesenchymal domains of combinatorial Dlx gene expression. Our data suggest that vertebrate jaw, hyoid and gill arch cartilages are serially homologous, and were primitively patterned dorsoventrally by a common Dlx blueprint.
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