ArticleJournal of the National Cancer Institute2013
Screening outcomes in older US women undergoing multiple mammograms in community practice: does interval, age, or comorbidity score affect tumor characteristics or false positive rates?
Article in Journal of the National Cancer Institute, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Health benefits and harms of mammography screening in older women (75+ years)-a systematic review.British journal of cancer · 2024Pooled it
- Benefits and harms of annual, biennial, or triennial breast cancer mammography screening for women at average risk of breast cancer: a systematic review for the European Commission Initiative on Breast Cancer (ECIBC).British journal of cancer · 2022Pooled it
- Benefits and Harms of Screening Mammography by Comorbidity and Age: A Qualitative Synthesis of Observational Studies and Decision Analyses.Journal of general internal medicine · 2016Pooled it
- Guideline
- Benefits and Harms of Mammography Screening in 75 + Women to Inform Shared Decision-making: a Simulation Modeling Study.Journal of general internal medicine · 2024Article
- Clinician and patient perspectives on screening mammography among women age 75 and older: A pilot study of a novel decision aid.PEC innovation · 2023Article
- Patient, primary care provider, and stakeholder perspectives on mammography screening frequency: lessons learned from a qualitative study.BMC cancer · 2022Article
- Cumulative Advanced Breast Cancer Risk Prediction Model Developed in a Screening Mammography Population.Journal of the National Cancer Institute · 2022Article
- Cumulative Probability of False-Positive Results After 10 Years of Screening With Digital Breast Tomosynthesis vs Digital Mammography.JAMA network open · 2022Observational
- Breast biopsy patterns and findings among older women undergoing screening mammography: The role of age and comorbidity.Journal of geriatric oncology · 2022Article
- Cost-Effectiveness of Screening Mammography Beyond Age 75 Years : A Cost-Effectiveness Analysis.Annals of internal medicine · 2022Article
- Cancer Screening Among Older Adults: a Geriatrician's Perspective on Breast, Cervical, Colon, Prostate, and Lung Cancer Screening.Current oncology reports · 2020Review
- Screening Mammography Outcomes: Risk of Breast Cancer and Mortality by Comorbidity Score and Age.Journal of the National Cancer Institute · 2020Article
- Annual vs Biennial Screening: Diagnostic Accuracy Among Concurrent Cohorts Within the Ontario Breast Screening Program.Journal of the National Cancer Institute · 2020Article
- Comorbid chronic diseases and cancer diagnosis: disease-specific effects and underlying mechanisms.Nature reviews. Clinical oncology · 2019Review
- Optimizing selection of candidates for lung cancer screening: role of comorbidity, frailty and life expectancy.Translational lung cancer research · 2019Article
- Factors Associated with False Positive Results on Screening Mammography in a Population of Predominantly Hispanic Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Article
- Family History and Breast Cancer Risk Among Older Women in the Breast Cancer Surveillance Consortium Cohort.JAMA internal medicine · 2018Article
- The Challenges of Screening Mammography in Racial/Ethnic Minority Populations in the United States: A mini-review and observations from a predominantly Hispanic community.Journal of cancer treatment & diagnosis · 2018Article
- Use of Surveillance Mammography Among Older Breast Cancer Survivors by Life Expectancy.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Background Uncertainty exists about the appropriate use of screening mammography among older women because comorbid illnesses may diminish the benefit of screening. We examined the risk of adverse tumor characteristics and false positive rates according to screening interval, age, and comorbidity. Methods From January 1999 to December 2006, data were collected prospectively on 2993 older women with breast cancer and 137 949 older women without breast cancer who underwent mammography at facilities that participated in a data linkage between the Breast Cancer Surveillance Consortium and Medicare claims. Women were aged 66 to 89 years at study entry to allow for measurement of 1 year of preexisting illnesses. We used logistic regression analyses to calculate the odds of advanced (IIb, III, IV) stage, large (>20 millimeters) tumors, and 10-year cumulative probability of false-positive mammography by screening frequency (1 vs 2 years), age, and comorbidity score. The comorbidity score was derived using the Klabunde approximation of the Charlson score. All statistical tests were two-sided. Results Adverse tumor characteristics did not differ statistically significantly by comorbidity, age, or interval. Cumulative probability of a false-positive mammography result was higher among annual screeners than biennial screeners irrespective of comorbidity: 48.0% (95% confidence interval [CI] = 46.1% to 49.9%) of annual screeners aged 66 to 74 years had a false-positive result compared with 29.0% (95% CI = 28.1% to 29.9%) of biennial screeners. Conclusion Women aged 66 to 89 years who undergo biennial screening mammography have similar risk of advanced-stage disease and lower cumulative risk of a false-positive recommendation than annual screeners, regardless of comorbidity.
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