Evidence map›Paper›PMID 23385153›Full record

Trial reportGynecologic oncology2013

The Peru Cervical Cancer Prevention Study (PERCAPS): the technology to make screening accessible.

Kimberly L Levinson, Carolina Abuelo, Jorge Salmeron, Eunice Chyung, Jing Zou, Suzanne E Belinson, Guixiang Wang, Carlos Santos Ortiz, Carlos Santiago Vallejos, Jerome L Belinson

Abstract readClinical Trial
In one paragraph

Trial report in Gynecologic oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Social innovation in diagnostics: three case studies.Infectious diseases of poverty · 2020
    Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Kimberly L LevinsonThe Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH 44195, USA. kimlynnlev@gmail.com
Carolina Abuelo
Jorge Salmeron
Eunice Chyung
Jing Zou
Suzanne E Belinson
Guixiang Wang
Carlos Santos Ortiz
Carlos Santiago Vallejos
Jerome L Belinson
EsSALUD · PEBGI Group (China) · CNCase Western Reserve University · USCleveland Clinic · USCleveland Clinic Lerner College of Medicine · USMexican Social Security Institute · MX

Funding

Fogarty International Clinical Research Scholars Support Center @ Vanderbilt-AAMCR24TW007988 · FIC · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2007 to 2011
$27.6M
FIC NIH HHS R24 TW007988
6 · The paper itself

Abstract

objectiveThis study utilized a combination of HPV self-sampling, iFTA elute specimen cards, and long distance transport for centralized processing of specimens to determine the feasibility of large-scale screening in remote and transient populations.

methodsThis study was performed in two locations in Peru (Manchay and Iquitos). The "Just For Me" cervico-vaginal brush and iFTA elute cards were used for the collection and transport of specimens. Samples were shipped via FedEx to China and tested for 14 types of high-risk HPV using PCR based MALDI-TOF. HPV positive women were treated with cryotherapy after VIA triage, and followed-up with colposcopy, biopsy, ECC, and repeat HPV testing at 6 months.

resultsSix hundred and forty three women registered, and 632 returned a sample over a 10 day period. Within 2 weeks, specimens were shipped, samples tested, and results received by study staff. Sixty-eight women (10.8%) tested positive, and these results were delivered over 4 days. Fifty-nine HPV positive women (87%) returned for evaluation and treatment, and 2 had large lesions not suitable for cryotherapy. At 6 months, 42 women (74%) returned for follow-up, and 3 had CIN 2 (all positive samples from the endocervical canal). Ninety eight percent of participants reported that they would participate in this type of program again.

conclusionsUtilizing HPV self-sampling, solid media specimen cards for long distance transport, and centralized high throughput processing, we achieved rapid delivery of results, high satisfaction levels, and low loss to follow-up for cervical cancer screening in remote and transient populations.

Indexed as

AdultCryotherapyEarly Detection of CancerFeasibility StudiesFemaleFollow-Up StudiesHealth Services AccessibilityHuman Papillomavirus DNA TestsHumansLost to Follow-UpMass ScreeningPapillomavirus InfectionsPatient SatisfactionPeruRural Health ServicesSpecimen Handling

Identifiers

PMID23385153
PMCPMC3632388
OpenAlexW2048156415

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.