Evidence map›Paper›PMID 23384804›Full record

ReviewBest practice & research. Clinical gastroenterology2012

Diarrhoea due to small bowel diseases.

Joseph A Murray, Alberto Rubio-Tapia

Abstract readReview
In one paragraph

Review in Best practice & research. Clinical gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Whipple Disease With Central Nervous System Involvement.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Open-Capsule Budesonide for Refractory Celiac Disease.The American journal of gastroenterology · 2017
    Article
  7. Article
  8. Review: chronic and persistent diarrhea with a focus in the returning traveler.Tropical diseases, travel medicine and vaccines · 2017
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joseph A MurrayDivision of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. Murray.joseph@mayo.edu
Alberto Rubio-Tapia
Mayo Clinic · US

Funding

EPIDEMIOLOGY OF CELIAC DISEASE--A POPULATION BASED STUDYR01DK057892 · NIDDK · MAYO CLINIC ROCHESTER · PI MURRAY, JOSEPH A · 2000 to 2010
$3.9M
A HLA Mouse Model for Gluten Sensitivity and EnteropathyR01DK071003 · NIDDK · MAYO CLINIC ROCHESTER · PI MURRAY, JOSEPH A · 2006 to 2009
$1.1M
NIDDK NIH HHS R01 DK057892NIDDK NIH HHS R01 DK071003
6 · The paper itself

Abstract

Small intestinal diseases are a common, though often overlooked cause of diarrhoeal illness. Fully 1% of the Caucasian population are affected by coeliac disease and a substantial portion of children living in poverty in the developing world are affected by environmental enteropathy. These are but two examples of the many diseases that cause mucosal injury to the primary digestive and absorptive organ in our body. While diarrhoea may be a common, though not universally seen symptom of small bowel mucosal disease, the consequent malabsorption can lead to substantial malnutrition and nutrient deficiencies. The small intestine, unlike the colon, has been relatively inaccessible, and systematic evaluation is often necessary to identify and treat small intestinal mucosal diseases that lead to diarrhoea. Immunodeficiency states, including HIV enteropathy, adult autoimmune enteropathy, drug-associated enteropathy, and tropical sprue continue to occur and require specific therapy. All patients with severe diarrhoea or diarrhoea associated with features suggestive of malabsorption may have a disease of the small intestinal mucosa that requires careful evaluation and targeted management.

Indexed as

Intestine, SmallAlgorithmsAnti-Bacterial AgentsBlind Loop SyndromeCeliac DiseaseChronic DiseaseDiarrheaHumansMalabsorption SyndromesPolyendocrinopathies, AutoimmuneSprue, TropicalWhipple DiseaseAnti-Bacterial Agents

Identifiers

PMID23384804
PMCPMC3621726
OpenAlexW2123074125

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.