ArticleScientific reports2013
Simple super-resolution live-cell imaging based on diffusion-assisted Förster resonance energy transfer.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 54 citations in OpenAlex.
- Article
- Cusp-artifacts in high order superresolution optical fluctuation imaging.Biomedical optics express · 2020Article
- Moments reconstruction and local dynamic range compression of high order superresolution optical fluctuation imaging.Biomedical optics express · 2019Article
- Lightsheet localization microscopy enables fast, large-scale, and three-dimensional super-resolution imaging.Communications biology · 2019Article
- SRRF: Universal live-cell super-resolution microscopy.The international journal of biochemistry & cell biology · 2018Article
- Super-resolution three-dimensional fluorescence and optical diffraction tomography of live cells using structured illumination generated by a digital micromirror device.Scientific reports · 2018Article
- Elucidating endotoxin-biomolecule interactions with FRET: extending the frontiers of their supramolecular complexation.Journal of biological methods · 2017Review
- Review
- Coumarin Push-Pull NLOphores with Red Emission: Solvatochromic and Theoretical Approach.Journal of fluorescence · 2016Article
- AIE Based Coumarin Chromophore - Evaluation and Correlation Between Solvatochromism and Solvent Polarity Parameters.Journal of fluorescence · 2016Article
- Model-free uncertainty estimation in stochastical optical fluctuation imaging (SOFI) leads to a doubled temporal resolution.Biomedical optics express · 2016Article
- Superresolution imaging with optical fluctuation using speckle patterns illumination.Scientific reports · 2015Article
- Novel approach for label free super-resolution imaging in far field.Scientific reports · 2015Article
- Rigid Coumarins: a Complete DFT, TD-DFT and Non Linear Optical Property Study.Journal of fluorescence · 2015Article
- Fast super-resolution imaging with ultra-high labeling density achieved by joint tagging super-resolution optical fluctuation imaging.Scientific reports · 2015Article
- Live-cell multiplane three-dimensional super-resolution optical fluctuation imaging.Nature communications · 2014Article
- Anomalous surface diffusion of protons on lipid membranes.Biophysical journal · 2014Article
- Towards the Physics of Calcium Signalling in Plants.Plants (Basel, Switzerland) · 2013Review
- Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications.Sensors (Basel, Switzerland) · 2013Article
- Phanta: a non-fluorescent photochromic acceptor for pcFRET.PloS one · 2013Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the recent development of several super-resolution fluorescence microscopic techniques, there are still few techniques that can be readily employed in conventional imaging systems. We present a very simple, rapid, general and cost-efficient super-resolution imaging method, which can be directly employed in a simple fluorescent imaging system with general fluorophores. Based on diffusion-assisted Förster resonance energy transfer (FRET), fluorescent donor molecules that label specific target structures can be stochastically quenched by diffusing acceptor molecules, thereby temporally separating otherwise spatially overlapped fluorescence signals and allowing super-resolution imaging. The proposed method provides two- to three-fold-enhancement in spatial resolution, a significant optical sectioning property, and favorable temporal resolution in live-cell imaging. We demonstrate super-resolution live-cell dynamic imaging using general fluorophores in a standard epi-fluorescence microscope with light-emitting diode (LED) illumination. Due to the simplicity of this approach, we expect that the proposed method will prove an attractive option for super-resolution imaging.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.