ArticlePLoS neglected tropical diseases2013
National borders effectively halt the spread of rabies: the current rabies epidemic in China is dislocated from cases in neighboring countries.
Article in PLoS neglected tropical diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Four genetically distinct types of rabies virus exist in Vietnam, including the SEA1 and SEA3 subclades within the Asian clade.Scientific reports · 2026Article
- Exploring one health-based strategies for rabies elimination: Overview and future prospects.PLoS neglected tropical diseases · 2025Review
- Rabies Virus Regulates Inflammatory Response in BV-2 Cells through Activation of Myd88 and NF-κB Signaling Pathways via TLR7.International journal of molecular sciences · 2024Article
- Bardoxolone methyl inhibits the infection of rabies virus via Nrf2 pathway activation in vitro.Virology journal · 2023Article
- Identifying high-risk areas for dog-mediated rabies using Bayesian spatial regression.One health (Amsterdam, Netherlands) · 2022Article
- Genetic Diversity, Evolutionary Dynamics, and Pathogenicity of Ferret Badger Rabies Virus Variants in Mainland China, 2008-2018.Frontiers in microbiology · 2022Article
- Article
- On the Use of Phylogeographic Inference to Infer the Dispersal History of Rabies Virus: A Review Study.Viruses · 2021Review
- Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review.PLoS neglected tropical diseases · 2021Article
- Animal Rabies Surveillance, China, 2004-2018.Emerging infectious diseases · 2020Article
- Portable Rabies Virus Sequencing in Canine Rabies Endemic Countries Using the Oxford Nanopore MinION.Viruses · 2020Article
- The reemergence of human rabies and emergence of an Indian subcontinent lineage in Tibet, China.PLoS neglected tropical diseases · 2019Article
- The role of socioeconomic and climatic factors in the spatio-temporal variation of human rabies in China.BMC infectious diseases · 2018Article
- Epidemiological and Genetic Characteristics of Rabies Virus Transmitted Through Organ Transplantation.Frontiers in cellular and infection microbiology · 2018Article
- Cross-border spread, lineage displacement and evolutionary rate estimation of rabies virus in Yunnan Province, China.Virology journal · 2017Article
- Modeling the transmission dynamics and control of rabies in China.Mathematical biosciences · 2017Review
- Large-Scale Phylogenomic Analysis Reveals the Complex Evolutionary History of Rabies Virus in Multiple Carnivore Hosts.PLoS pathogens · 2016Article
- Modeling the geographic spread of rabies in China.PLoS neglected tropical diseases · 2015Article
- Animal-associated exposure to rabies virus among travelers, 1997-2012.Emerging infectious diseases · 2015Article
- The spatiotemporal expansion of human rabies and its probable explanation in mainland China, 2004-2013.PLoS neglected tropical diseases · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
China has seen a massive resurgence of rabies cases in the last 15 years with more than 25,000 human fatalities. Initial cases were reported in the southwest but are now reported in almost every province. There have been several phylogenetic investigations into the origin and spread of the virus within China but few reports investigating the impact of the epidemic on neighboring countries. We therefore collected nucleoprotein sequences from China and South East Asia and investigated their phylogenetic and phylogeographic relationship. Our results indicate that within South East Asia, isolates mainly cluster according to their geographic origin. We found evidence of sporadic exchange of strains between neighboring countries, but it appears that the major strain responsible for the current Chinese epidemic has not been exported. This suggests that national geographical boundaries and border controls are effective at halting the spread of rabies from China into adjacent regions. We further investigated the geographic structure of Chinese sequences and found that the current epidemic is dominated by variant strains that were likely present at low levels in previous domestic epidemics. We also identified epidemiological linkages between high incidence provinces consistent with observations based on surveillance data from human rabies cases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.