ArticlePloS one2013
A stochastic model for electron multiplication charge-coupled devices--from theory to practice.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
40 citing papers in PubMed, 119 citations in OpenAlex.
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- Approaching maximum resolution in structured illumination microscopy via accurate noise modeling.Npj imaging · 2025Article
- State of the art medical devices for fluorescence-guided surgery (FGS): technical review and future developments.Surgical endoscopy · 2024Review
- BNP-Track: a framework for superresolved tracking.Nature methods · 2024Article
- Approaching Maximum Resolution in Structured Illumination Microscopy via Accurate Noise Modeling.bioRxiv : the preprint server for biology · 2024Article
- On the statistical foundation of a recent single molecule FRET benchmark.Nature communications · 2024Article
- Short-wave Infrared Photoluminescence Lifetime Mapping of Rare-Earth Doped Nanoparticles Using All-Optical Streak Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Photophysical image analysis: Unsupervised probabilistic thresholding for images from electron-multiplying charge-coupled devices.PloS one · 2024Article
- Tracking the Activity and Position of Mitochondrial β-Barrel Proteins.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Physically informed Monte Carlo simulation of dual-wedge prism-based spectroscopic single-molecule localization microscopy.Journal of biomedical optics · 2024Article
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- Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy.Nanomaterials (Basel, Switzerland) · 2023Article
- Emergence of Raman Spectroscopy as a Probing Tool for Theranostics.Nanotheranostics · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Electron multiplication charge-coupled devices (EMCCD) are widely used for photon counting experiments and measurements of low intensity light sources, and are extensively employed in biological fluorescence imaging applications. These devices have a complex statistical behaviour that is often not fully considered in the analysis of EMCCD data. Robust and optimal analysis of EMCCD images requires an understanding of their noise properties, in particular to exploit fully the advantages of Bayesian and maximum-likelihood analysis techniques, whose value is increasingly recognised in biological imaging for obtaining robust quantitative measurements from challenging data. To improve our own EMCCD analysis and as an effort to aid that of the wider bioimaging community, we present, explain and discuss a detailed physical model for EMCCD noise properties, giving a likelihood function for image counts in each pixel for a given incident intensity, and we explain how to measure the parameters for this model from various calibration images.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.