Evidence map›Paper›PMID 23382812›Full record

ArticlePloS one2013

Molecular evidence of lateral gene transfer in rpoB gene of Mycobacterium yongonense strains via multilocus sequence analysis.

Byoung-Jun Kim, Seok-Hyun Hong, Yoon-Hoh Kook, Bum-Joon Kim

Abstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Broad-range amplification and sequencing of theJournal of clinical microbiology · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Role of the DNA Mismatch Repair GeneFrontiers in microbiology · 2017
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Mycobacterium yongonense in pulmonary disease, Italy.Emerging infectious diseases · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Byoung-Jun KimDepartment of Microbiology and Immunology, Seoul National University Medical Research Center (SNUMRC), Seoul National University College of Medicine, Seoul, Republic of Korea.
Seok-Hyun Hong
Yoon-Hoh Kook
Bum-Joon Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, a novel species, Mycobacterium yongonense (DSM 45126(T)), was introduced and while it is phylogenetically related to Mycobacterium intracellulare, it has a distinct RNA polymerase β-subunit gene (rpoB) sequence that is identical to that of Mycobacterium parascrofulaceum, which is a distantly related scotochromogen, which suggests the acquisition of the rpoB gene via a potential lateral gene transfer (LGT) event. The aims of this study are to prove the presence of the LGT event in the rpoB gene of the M. yongonense strains via multilocus sequence analysis (MLSA). In order to determine the potential of an LGT event in the rpoB gene of the M. yongonense, the MLSA based on full rpoB sequences (3447 or 3450 bp) and on partial sequences of five other targets [16S rRNA (1383 or 1395 bp), hsp65 (603 bp), dnaJ (192 bp), recA (1053 bp), and sodA (501 bp)] were conducted. Incongruences between the phylogenetic analysis of the full rpoB and the five other genes in a total of three M. yongonense strains [two clinical strains (MOTT-12 and MOTT-27) and one type strain (DSM 45126(T))] were observed, suggesting that rpoB gene of three M. yongonense strains may have been acquired very recently via an LGT event from M. parascrofulaceum, which is a distantly related scotochromogen.

Indexed as

Gene Transfer, HorizontalSequence Analysis, DNABacterial ProteinsDNA-Directed RNA PolymerasesHumansMultilocus Sequence TypingMycobacterium avium ComplexNontuberculous MycobacteriaPhylogenyRNA, Ribosomal, 16SBacterial ProteinsDNA-Directed RNA PolymerasesRNA, Ribosomal, 16SrpoB protein, Mycobacterium tuberculosis

Identifiers

PMID23382812
PMCPMC3561371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.