Evidence map›Paper›PMID 23380666›Full record

ArticleThe Pediatric infectious disease journal2013

The epidemiology and clinical characteristics of young children hospitalized with respiratory syncytial virus infections in Guatemala (2007-2010).

Gayle Fischer Langley, John McCracken, Wences Arvelo, Alejandra Estevez, Gissela Villarruel, Mila Prill, Marika Iwane, Jennifer Gray, Fabiola Moscoso, Lissette Reyes and 3 more

Abstract read
In one paragraph

Article in The Pediatric infectious disease journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  4. Review
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  7. Article
  8. Assessing the Incidence of Symptomatic Respiratory Syncytial Virus Illness Within a Prospective Birth Cohort in Managua, Nicaragua.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  9. Article
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  11. Detection of Multiple Respiratory Viruses Associated With Mortality and Severity of Illness in Children.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Gayle Fischer LangleyDivision of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. fez7@cdc.gov
John McCracken
Wences Arvelo
Alejandra Estevez
Gissela Villarruel
Mila Prill
Marika Iwane
Jennifer Gray
Fabiola Moscoso
Lissette Reyes
Juan Carlos Moir
Jose Ortiz
Kim Lindblade

Funding

CGH CDC HHS 1U01GH000028-03CGH CDC HHS U01 GH000028Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundThere have been few population-based studies from Central America on respiratory syncytial virus (RSV) infections in young children. We report population-based incidence rates and describe epidemiological and clinical characteristics of children <5 years old hospitalized with RSV infections in Guatemala.

methodsProspective, active hospital-based surveillance for acute respiratory infections in children <5 years old was conducted at 3 hospitals in Guatemala from November 2007 through July 2010. RSV hospitalization rates were calculated for areas where the catchment population could be defined. Comparisons were made between children who were RSV-positive and RSV-negative.

resultsRSV was detected in 549 (25%) of enrolled children. Overall, annual rates of RSV hospitalizations ranged from 5.9 to 45.9 and 2.0 to 13.7 per 1000 children <1 year old and <5 years old, respectively, but varied by location and calendar year. Rates generally decreased with age--children <6 months had rates up to 30 times higher than older children, but children >12 months old still had rates up to 5.5 per 1000 per year and accounted for 42% of deaths. Children with RSV infections were more likely to have signs of respiratory distress (85% versus 63%, P < 0.001) compared with those without RSV infections, but case fatality ratios were similar (3-4%).

conclusionsThe large burden and severity of RSV infections in young Guatemalan children is similar in magnitude and age distribution to RSV disease burdens found in other developing countries and suggests that this population would benefit from prevention strategies, including vaccines against RSV that are currently under development.

Indexed as

Age DistributionChild, PreschoolFemaleGuatemalaHospitalizationHospitalsHumansIncidenceInfantInfant, NewbornMaleProspective StudiesRespiratory Distress SyndromeRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus Infections

Identifiers

PMID23380666
PMCPMC10942251

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.