Evidence map›Paper›PMID 23380045›Full record

ArticleAmerican journal of epidemiology2013

Dairy-food, calcium, magnesium, and vitamin D intake and endometriosis: a prospective cohort study.

Holly R Harris, Jorge E Chavarro, Susan Malspeis, Walter C Willett, Stacey A Missmer

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in American journal of epidemiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06289257 (Analysis of Vitamin D and VDR Expression in Women With Advanced Endometriosis), which is not on this map. Cited by 86 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 5 pooled it
17.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06289257 completednot on this mapstarted 2024, after this paper: background citation

Analysis of Vitamin D and VDR Expression in Women With Advanced Endometriosis: A Case-Control Study in Thailand

Typeobservational_patient_registrySponsorKhon Kaen UniversityRan2024 to 2024Enrolled108ConditionsEndometriosis, Vitamin D Deficiency/Insufficiency, Vitamin D StatusArmsVitamin D level, Vitamin D receptor
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 5 syntheses or guidelines pooled it, 218 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Vitamin D and assisted reproduction technologies: current concepts.Reproductive biology and endocrinology : RB&E · 2014
    Pooled it
  6. Trial
  7. Trial
  8. Effects of Vitamin D on Endometriosis-Related Pain: A Double-Blind Clinical Trial.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Trial
  9. Predictive markers of endometriosis: a future perspective.Archives of gynecology and obstetrics · 2026
    Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Observational
  16. 1,25-Dihydroxy vitamin DAnnals of medicine · 2025
    Article
  17. Article
  18. Review
  19. Review
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Holly R HarrisDepartment of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, MA 02115, USA. hharris3@partners.org
Jorge E Chavarro
Susan Malspeis
Walter C Willett
Stacey A Missmer
Brigham and Women's Hospital · US

Funding

Risk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3M
Training Program in Environmental EpidemiologyT32ES007069 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI LADEN, FRANCINE · 1985 to 2024
$13.9M
Immunology, Inflammation, and EndometriosisR01HD057210 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2009 to 2012
$1.4M
Endogenous Hormones and Risk of EndometriosisR01HD052473 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2006 to 2009
$1.1M
A prospective study of diet and endometriosisR03HD048544 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2005 to 2006
$173k
NCI NIH HHS CA50385NCI NIH HHS R01 CA050385NICHD NIH HHS HD48544NICHD NIH HHS HD52473NICHD NIH HHS HD57210NICHD NIH HHS R01 HD052473NICHD NIH HHS R01 HD057210NICHD NIH HHS R03 HD048544NIEHS NIH HHS T32 ES007069PHS HHS 5T76MC00001
6 · The paper itself

Abstract

The etiology of endometriosis is poorly understood, and few modifiable risk factors have been identified. Dairy foods and some nutrients can modulate inflammatory and immune factors, which are altered in women with endometriosis. We investigated whether intake of dairy foods, nutrients concentrated in dairy foods, and predicted plasma 25-hydroxyvitamin D (25(OH)D) levels were associated with incident laparoscopically confirmed endometriosis among 70,556 US women in Nurses' Health Study II. Diet was assessed via food frequency questionnaire. A score for predicted 25(OH)D level was calculated for each participant. During 737,712 person-years of follow-up over a 14-year period (1991-2005), 1,385 cases of incident laparoscopically confirmed endometriosis were reported. Intakes of total and low-fat dairy foods were associated with a lower risk of endometriosis. Women consuming more than 3 servings of total dairy foods per day were 18% less likely to be diagnosed with endometriosis than those reporting 2 servings per day (rate ratio = 0.82, 95% confidence interval: 0.71, 0.95; P(trend) = 0.03). In addition, predicted plasma 25(OH)D level was inversely associated with endometriosis. Women in the highest quintile of predicted vitamin D level had a 24% lower risk of endometriosis than women in the lowest quintile (rate ratio = 0.76, 95% confidence interval: 0.60, 0.97; P(trend) = 0.004). Our findings suggest that greater predicted plasma 25(OH)D levels and higher intake of dairy foods are associated with a decreased risk of endometriosis.

Indexed as

Dairy ProductsDietAdultBody Mass IndexCalcium, DietaryCohort StudiesDiet SurveysEndometriosisFemaleFollow-Up StudiesHumansMagnesiumMiddle AgedParityProspective StudiesRegression Analysis25-hydroxyvitamin DCalcium, DietaryMagnesiumVitamin DVitamins

Identifiers

PMID23380045
PMCPMC3626048
OpenAlexW2120100033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.