Trial reportJournal of consulting and clinical psychology2013
Fixable or fate? Perceptions of the biology of depression.
Trial report in Journal of consulting and clinical psychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03998748 (Electrophysiological Correlates of Cognition in Depression), which is not on this map. Cited by 48 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Electrophysiological Correlates of Cognition in Depression
Who cites it
48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 168 citations in OpenAlex.
- The serotonin theory of depression: a systematic umbrella review of the evidence.Molecular psychiatry · 2023Pooled it
- Perceptions of ADHD Among Diagnosed Children and Their Parents: A Systematic Review Using the Common-Sense Model of Illness Representations.Clinical child and family psychology review · 2018Pooled it
- Schoolhouse risk: Can we mitigate the polygenic Pygmalion effect?Acta psychologica · 2024Trial
- Framing Effects of Cognitive Behavioural Therapy for Depression on Perceptions of Believability, Acceptability, and Credibility.International journal of environmental research and public health · 2023Trial
- Limited impacts of biogenetic messaging on neural correlates of cognitive control and beliefs about depression.Cognitive, affective & behavioral neuroscience · 2023Trial
- Testing positive for a genetic predisposition to depression magnifies retrospective memory for depressive symptoms.Journal of consulting and clinical psychology · 2017Trial
- Polygenic risk scores are not genetic predispositions.Nature human behaviour · 2026Article
- Impact of a Genetic Diagnosis for a Child's Autism on Parental Perceptions.Journal of autism and developmental disorders · 2025Article
- Shortening duration of untreated illness in young people with first episode eating disorders: protocol of a randomised controlled feasibility trial of a smartphone friendly multi-modal decision-making tool (FREED-M) to improve help-seeking.Pilot and feasibility studies · 2025Article
- Implications of Genetic Attributions for Addiction in Adults Affected by Alcohol Use Disorder and Gambling Disorder.Addiction research & theory · 2025Article
- Are You a Closet Dualist? Evidence From Brief Implicit Association Task.Open mind : discoveries in cognitive science · 2025Article
- Examining parents' perceptions of their children's autism and completion of genetic testing.International journal of developmental disabilities · 2025Article
- Commentary: Perspectives on ADHD in children and adolescents as a social construct amidst rising prevalence of diagnosis and medication use.Frontiers in psychiatry · 2024Article
- The Ethics of Risk Prediction for Psychosis and Suicide Attempt in Youth Mental Health.The Journal of pediatrics · 2023Review
- Biology, Society, or Choice: How Do Non-Experts Interpret Explanations of Behaviour?Open mind : discoveries in cognitive science · 2023Article
- Is the mainstream construction of mood disorders resistant to systemic thinking?Frontiers in psychiatry · 2023Article
- Interactive Beliefs about Genes and Behavior Predict Improved Sun Protection Following Melanoma Genetic Counseling.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022Article
- The symptom discounting effect: what to do when negative genetic test results become risk factors for alcohol use disorder.Scientific reports · 2022Article
- The effect of neuroscientific evidence on sentencing depends on how one conceives of reasons for incarceration.PloS one · 2022Article
- Relationships of biomedical beliefs about depression to treatment-related expectancies in a treatment-seeking sample.Psychotherapy (Chicago, Ill.) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
objectivePrevious research has shown that biological (e.g., genetic, biochemical) accounts of depression--currently in ascendancy--are linked to the general public's pessimism about the syndrome's prognosis. This research examined for the first time whether people with depressive symptoms would associate biological accounts of depression with pessimism about their own prognoses and whether a psychoeducation intervention portraying the biology of depression as malleable could decrease prognostic pessimism among symptomatic individuals.
methodIn 3 studies, participants were recruited online and assessed for depression symptoms. Those with significant depressive symptomatology (a Beck Depression Inventory-II score of at least 16) rated their endorsement of biochemical and genetic causal attributions for their symptoms and indicated expected length of symptom duration. An audiovisual intervention emphasizing the malleability of gene effects and neurochemistry was developed, and its effects on symptomatic individuals' prognostic pessimism, feelings of agency, guilt, and general hopelessness were measured.
resultsBiochemical and genetic causal attributions for depression were significantly associated with prognostic pessimism among symptomatic individuals. The malleability intervention significantly reduced prognostic pessimism, increased feelings of agency, and decreased general hopelessness.
conclusionsBiochemical and genetic attributions for depression are related to prognostic pessimism among individuals with depressive symptoms, and not just among the general public. However, emphasizing the malleability of gene effects and brain chemistry in depression can foster more optimism about depression-related beliefs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.