ArticleNorth American journal of medical sciences2013
Serum Cholesterol and Ceruloplasmin Levels in Second Trimester can Predict Development of Pre-eclampsia.
Article in North American journal of medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Maternal hyperlipidemia and the risk of preeclampsia: a meta-analysis.American journal of epidemiology · 2014Pooled it
- Lipid profile and cytokines in hypertension of pregnancy: A comparison of preeclampsia therapies.Journal of clinical hypertension (Greenwich, Conn.) · 2018Trial
- Pathophysiology of Maternal Obesity and Hypertension in Pregnancy.Journal of cardiovascular development and disease · 2025Review
- Prediction model for severe maternal morbidity in pregnant women with hypertensive disorders of pregnancy.Pakistan journal of medical sciences · 2024Article
- Risk Prediction Model of Early-Onset Preeclampsia Based on Risk Factors and Routine Laboratory Indicators.Life (Basel, Switzerland) · 2023Article
- Preeclampsia and Obesity-The Preventive Role of Exercise.International journal of environmental research and public health · 2023Review
- Molecular Functions of Ceruloplasmin in Metabolic Disease Pathology.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Review
- Obesity and Preeclampsia: Common Pathophysiological Mechanisms.Frontiers in physiology · 2018Review
- Increased risk for the development of preeclampsia in obese pregnancies: weighing in on the mechanisms.American journal of physiology. Regulatory, integrative and comparative physiology · 2015Review
- Evaluation of high-sensitivity C-reactive protein and serum lipid profile in southeastern Nigerian women with pre-eclampsia.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2015Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPre-eclampsia is one of the leading causes of high rates of maternal and perinatal mortality and morbidity. Pathophysiology of pre-eclampsia is still obscure. Currently, there are no screening tests for pre-eclampsia that are reliable, valid, and economical. Parameters of oxidative stress could be early markers of endothelial dysfunction that predates clinical pre-eclampsia.
aimThis study was to study ceruloplasmin in nulliparous women as marker of oxidative stress and lipid profile to evaluate their value in prediction of pre-eclampsia. MATERIALS AND
methodsProspective observational study. 306 nulliparous women had their serum lipid profile and ceruloplasmin levels measured at 14-16 weeks period of gestation as sample 1 and at 18-20 weeks as sample 2. All cases were followed up till the end of pregnancy for development of pre-eclampsia.
resultsThere was no statistically significant difference between the normals and pre-eclampsia cases at 14-16 week for all the oxidative stress parameters (P > 0.05), but at 18-20 week, there was statistically significant difference between the normals and pre-eclampsia cases in cholesterol and ceruloplasmin parameters (P < 0.05).
conclusionCholesterol and ceruloplasmin levels in second trimester (18-20 weeks) can predict the development of pre-eclampsia.
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