ArticleFrontiers in integrative neuroscience2013
Quantification of anisotropy and fiber orientation in human brain histological sections.
Article in Frontiers in integrative neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.
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Who cites it
92 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Considerations and recommendations from the ISMRM diffusion study group for preclinical diffusion MRI: Part 2-Ex vivo imaging: Added value and acquisition.Magnetic resonance in medicine · 2025Guideline
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- Not All Spikes Are Equal.Journal of clinical medicine · 2025Review
- Validation of structure tensor analysis for orientation estimation in brain tissue microscopy.Journal of neuroscience methods · 2025Article
- White Matter Geometry Confounds Diffusion Tensor Imaging Along Perivascular Space (DTI-ALPS) Measures.Human brain mapping · 2025Article
- 3D MERMAID: 3D Multi-shot enhanced recovery motion artifact insensitive diffusion for submillimeter, multi-shell, and SNR-efficient diffusion imaging.Magnetic resonance in medicine · 2025Article
- Considerations and recommendations from the ISMRM Diffusion Study Group for preclinical diffusion MRI: Part 3-Ex vivo imaging: Data processing, comparisons with microscopy, and tractography.Magnetic resonance in medicine · 2025Review
- Revisiting the critical roles of reactive microglia in traumatic brain injury.International journal of surgery (London, England) · 2025Review
- Imaging the structural connectome with hybrid MRI-microscopy tractography.Medical image analysis · 2025Article
- Validation of Structure Tensor Analysis for Orientation Estimation in Brain Tissue Microscopy.bioRxiv : the preprint server for biology · 2025Article
- Advanced diffusion imaging in grey matter reflects individual differences in cognitive ability in older adults.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Frequency-specific functional difference between gyri and sulci in naturalistic paradigm fMRI.Brain structure & function · 2024Article
- Direct segmentation of cortical cytoarchitectonic domains using ultra-high-resolution whole-brain diffusion MRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Temporal fingerprints of cortical gyrification in marmosets and humans.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- An open resource combining multi-contrast MRI and microscopy in the macaque brain.Nature communications · 2023Article
- Gyral peaks and patterns in human brains.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Cortex2vector: anatomical embedding of cortical folding patterns.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Mapping astrogliosis in the individual human brain using multidimensional MRI.Brain : a journal of neurology · 2023Article
- A comparison of altered white matter microstructure in youth born with congenital heart disease or born preterm.Frontiers in neurology · 2023Article
32 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
Diffusion weighted imaging (DWI) has provided unparalleled insight into the microscopic structure and organization of the central nervous system. Diffusion tensor imaging (DTI) and other models of the diffusion MRI signal extract microstructural properties of tissues with relevance to the normal and injured brain. Despite the prevalence of such techniques and applications, accurate and large-scale validation has proven difficult, particularly in the human brain. In this report, human brain sections obtained from a digital public brain bank were employed to quantify anisotropy and fiber orientation using structure tensor analysis. The derived maps depict the intricate complexity of white matter fibers at a resolution not attainable with current DWI experiments. Moreover, the effects of multiple fiber bundles (i.e., crossing fibers) and intravoxel fiber dispersion were demonstrated. Examination of the cortex and hippocampal regions validated-specific features of previous in vivo and ex vivo DTI studies of the human brain. Despite the limitation to two dimensions, the resulting images provide a unique depiction of white matter organization at resolutions currently unattainable with DWI. The method of analysis may be used to validate tissue properties derived from DTI and alternative models of the diffusion signal.
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