ReviewCold Spring Harbor perspectives in medicine2013
The prevention of thalassemia.
Review in Cold Spring Harbor perspectives in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
112 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion-dependent beta thalassaemia.The Cochrane database of systematic reviews · 2023Pooled it
- Epidemiology of Thalassemia in Gulf Cooperation Council Countries: A Systematic Review.BioMed research international · 2020Pooled it
- Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort.Journal of pediatric hematology/oncology · 2015Guideline
- Prenatal diagnosis of hemoglobinopathies by chorionic villus sampling: A large single-center experience.Turkish journal of obstetrics and gynecology · 2026Article
- Development and Internal Validation of a Machine Learning-Based Model for Thalassemia Identification Using Complete Blood Count Parameters.Diagnostics (Basel, Switzerland) · 2026Article
- α-Thalassemia in Oraons-indigenous tribal population from Jharkhand, India: insights to common deletions.Human genetics · 2026Article
- Spectrum of Hemoglobinopathies in Microcytic Hypochromic Anemia: A Cross-Sectional Study From Western India.Cureus · 2026Article
- Article
- Distribution of Abnormal Hemoglobins in Saudi Arabia: Analysis of Private Sector Laboratory Data.Journal of epidemiology and global health · 2026Article
- Thalassemia in Guangxi: current situation and future prospects.Frontiers in public health · 2026Article
- Genetic Heterogeneity of β-thalassemia Variants in Affected Filipinos.Acta medica Philippina · 2026Article
- A direct multiplex isothermal amplification-reverse dot blot hybridization system for β-thalassemia diagnosis.Annals of hematology · 2025Article
- Accurate diagnosis of hemoglobinopathies with machine learning based on high-throughput proteomics.HemaSphere · 2025Article
- From misconceptions to empowerment: assessing health and genetic literacy on thalassemia among Tunisian secondary school students.BMC public health · 2025Article
- Prenatal diagnosis of rare genetic disorders: fourteen years' experience of a tertiary genetic centre from India.Orphanet journal of rare diseases · 2025Article
- Genetic Profiling and frequencies of Modifiers in Transfusion-Dependent Thalassemia.Pakistan journal of medical sciences · 2025Article
- Genetic self-counselors in Tunisia: the role of health education in hemoglobinopathies prevention among high school students.Orphanet journal of rare diseases · 2025Article
- Synergic Treatment of Plant-Based Antioxidants with Iron Chelators for Iron Overload in Transfusion-Dependent-Thalassemia Patients: A Systematic Review.International journal of hematology-oncology and stem cell research · 2025Review
- Exploring the role of consanguinity in thalassemia prevalence in Pakistan: an in-depth analysis of genetic and cultural factors affecting public health.Annals of medicine and surgery (2012) · 2025Review
- Prevalence of common autosomal recessive and X-linked conditions in pregnant women in Vietnam: a cross-sectional study.Scientific reports · 2025Article
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The thalassemias are among the most common inherited diseases worldwide, affecting individuals originating from the Mediterranean area, Middle East, Transcaucasia, Central Asia, Indian subcontinent, and Southeast Asia. As the diseases require long-term care, prevention of the homozygous state constitutes a major armament in the management. This article discusses the major prevention programs that are set up in many countries in Europe, Asia, and Australia, often drawing from the experience in Sardinia. These comprehensive programs involve carrier detections, molecular diagnostics, genetic counseling, and prenatal diagnosis. Variability of clinical severity can be attributable to interactions with α-thalassemia and mutations that increase fetal productions. Special methods that are currently quite expensive and not widely applicable are preimplantation and preconception diagnosis. The recent successful studies of fetal DNA in maternal plasma may allow future prenatal diagnosis that is noninvasive for the fetus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.