Evidence map›Paper›PMID 23378527›Full record

ArticleJournal of aging and health2013

Depressive symptomatology, exercise adherence, and fitness are associated with reduced cognitive performance in heart failure.

Michael L Alosco, Mary Beth Spitznagel, Manfred van Dulmen, Naftali Raz, Ronald Cohen, Lawrence H Sweet, Lisa H Colbert, Richard Josephson, Joel Hughes, Jim Rosneck and 1 more

Abstract read
In one paragraph

Article in Journal of aging and health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
8.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Review
  6. Psychological Aspects of Heart Failure.Current cardiology reports · 2016
    Review
  7. Article
  8. The Role of Gratitude in Spiritual Well-being in Asymptomatic Heart Failure Patients.Spirituality in clinical practice (Washington, D.C.) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Michael L AloscoKent State University, Kent, OH 44242, USA. malosco@kent.edu
Mary Beth Spitznagel
Manfred van Dulmen
Naftali Raz
Ronald Cohen
Lawrence H Sweet
Lisa H Colbert
Richard Josephson
Joel Hughes
Jim Rosneck
John Gunstad
Kent State University · USSumma Akron City Hospital · USUniversity Hospitals Case Medical Center · USUniversity of Florida · USUniversity of Georgia · USUniversity of Wisconsin–Madison · USWayne State University · US

Funding

University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTIAAN LEEUWENBURGH · 2007 to 2026
$22.8M
Neural Correlates and Modifiers of Cognitive AgingR37AG011230 · NIA · WAYNE STATE UNIVERSITY · PI RAZ, NAFTALI · 2005 to 2014
$5.2M
Cognitive Benefits of Cardiac Rehabilitation in Heart FailureR01HL089311 · NHLBI · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2008 to 2012
$2.6M
Cognitive Effects of Bariatric SurgeryR01DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2006 to 2009
$1.5M
Extended Effects of Bariatric Surgery on Cognitive FunctionR56DK075119 · NIDDK · KENT STATE UNIVERSITY · PI GUNSTAD, JOHN J. · 2010 to 2010
$296k
NHLBI NIH HHS HL089311NHLBI NIH HHS R01 HL089311NIA NIH HHS P30 AG028740NIA NIH HHS R37 AG011230NIDDK NIH HHS DK075119NIDDK NIH HHS R01 DK075119NIDDK NIH HHS R56 DK075119
6 · The paper itself

Abstract

objectiveDepression is common in heart failure (HF) and associated with reduced cognitive function. The current study used structrual equation modeling to examine whether depression adversely impacts cognitive function in HF through its adverse affects on exercise adherence and cardiovascular fitness.

method158 HF patients completed neuropsychological testing, physical fitness test, Beck depression inventory-II (BDI-II), and measures assessing exercise adherence and physical exertion.

resultsThe model demonstrated excellent model fit and increased scores on the BDI-II negatively affected exercise adherence and cardiovascular fitness. There was a strong inverse association between cardiovascular fitness and cognitive function. Sobel test showed a significant indirect pathway between the BDI-II and cognitive function through cardiovascular fitness. DISCUSSION: This study suggests depression in HF may adversely impact cognitive function through reduced cardiovascular fitness. Prospective studies are needed to determine whether treatment of depression can lead to better lifestyle behaviors and ultimately improve neurocognitive outcomes in HF.

Indexed as

AgedAged, 80 and overCognition DisordersDepressionExerciseFemaleHeart FailureHumansMaleMiddle AgedModels, PsychologicalPatient CompliancePhysical FitnessRisk Factors

Identifiers

PMID23378527
PMCPMC5022365
OpenAlexW2137525994

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.