Evidence map›Paper›PMID 23378290›Full record

ReviewWiley interdisciplinary reviews. RNA

The GA-minor submotif as a case study of RNA modularity, prediction, and design.

Wade W Grabow, Zhuoyun Zhuang, Joan-Emma Shea, Luc Jaeger

Open access · greenAbstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. RNA modularity for synthetic biology.F1000prime reports · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wade W GrabowDepartment of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA.
Zhuoyun Zhuang
Joan-Emma Shea
Luc Jaeger
University of California, Santa Barbara · US

Funding

Exploring the RNA syntax for engineering therapeutic RNA-based nano-factoriesR01GM079604 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI JAEGER, LUC · 2007 to 2011
$1.7M
NIGMS NIH HHS R01 GM079604NIGMS NIH HHS R01-GM079604
6 · The paper itself

Abstract

Complex natural RNAs such as the ribosome, group I and group II introns, and RNase P exemplify the fact that three-dimensional (3D) RNA structures are highly modular and hierarchical in nature. Tertiary RNA folding typically takes advantage of a rather limited set of recurrent structural motifs that are responsible for controlling bends or stacks between adjacent helices. Herein, the GA minor and related structural motifs are presented as a case study to highlight several structural and folding principles, to gain further insight into the structural evolution of naturally occurring RNAs, as well as to assist the rational design of artificial RNAs.

Indexed as

AnimalsHumansModels, MolecularNucleic Acid ConformationNucleotide MotifsRNARNA

Identifiers

PMID23378290
PMCPMC3815693
OpenAlexW1972073962

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.