ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2013
Recurrent seizures and serotonin syndrome following "2C-I" ingestion.
Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Sublethal Concentrations of 2C-I and 25I-NBOMe Designer Drugs ImpactInternational journal of molecular sciences · 2025Article
- Acute Effects of the Psychedelic Phenethylamine 25I-NBOMe in C57BL/6J Male Mice.International journal of molecular sciences · 2025Article
- Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders.International journal of environmental research and public health · 2022Article
- Human Neuronal Cell Lines as An In Vitro Toxicological Tool for the Evaluation of Novel Psychoactive Substances.International journal of molecular sciences · 2021Article
- Novel Psychoactive Phenethylamines: Impact on Genetic Material.International journal of molecular sciences · 2020Article
- Designer drugs: mechanism of action and adverse effects.Archives of toxicology · 2020Review
- Unexpected Serotonin Syndrome, Epileptic Seizures, and Cerebral Edema Following 2,5-dimethoxy-4-bromophenethylamine Ingestion.Journal of forensic sciences · 2019Article
- Management of severe arterial hypertension associated with serotonin syndrome: a case report analysis based on systematic review techniques.Therapeutic advances in psychopharmacology · 2019Article
- Comparison of the behavioral responses induced by phenylalkylamine hallucinogens and their tetrahydrobenzodifuran ("FLY") and benzodifuran ("DragonFLY") analogs.Neuropharmacology · 2019Article
- Neurochemical and Behavioral Profiling in Male and Female Rats of the Psychedelic Agent 25I-NBOMe.Frontiers in pharmacology · 2019Article
- Comparative neuropharmacology of N-(2-methoxybenzyl)-2,5-dimethoxyphenethylamine (NBOMe) hallucinogens and their 2C counterparts in male rats.Neuropharmacology · 2018Article
- Locomotor and discriminative stimulus effects of four novel hallucinogens in rodents.Behavioural pharmacology · 2017Article
- Pharmacology and Toxicology of N-Benzylphenethylamine ("NBOMe") Hallucinogens.Current topics in behavioral neurosciences · 2017Review
- NPS: Medical Consequences Associated with Their Intake.Current topics in behavioral neurosciences · 2017Review
- Legal highs: staying on top of the flood of novel psychoactive substances.Therapeutic advances in psychopharmacology · 2015Review
- Novel psychoactive substances of interest for psychiatry.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2015Article
- Behavioral and neurochemical pharmacology of six psychoactive substituted phenethylamines: mouse locomotion, rat drug discrimination and in vitro receptor and transporter binding and function.Psychopharmacology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The phenethylamines, including 2, 5 dimethoxy-4-iodophenethylamine, commonly referred to as 2C-I, have recently emerged as a new class of designer drugs. Cases of toxicity from these drugs are not well described in the literature. This case report describes a 19 year-old male who insufflated 2C-I. Following the ingestion, the patient developed recurrent seizures, and was taken to the emergency department, where he was noted to be hyperadrenergic and had recurrent seizures. The patient was diagnosed with serotonin syndrome and experienced prolonged respiratory failure, although he ultimately made a full recovery. Comprehensive drug testing revealed the presence of 2C-I. The pharmacologic properties of 2C-I are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.