Evidence map›Paper›PMID 23377782›Full record

SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2013

Defining postoperative ileus: results of a systematic review and global survey.

Ryash Vather, Sid Trivedi, Ian Bissett

4 registry-linked trialsAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 256 papers, 20 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
256citing papers in PubMed, 20 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04205058 nacompletednot on this mapstarted 2020, after this paper: background citation

Coffee After Pancreatic Surgery - a Randomised, Single Blinded, Placebo-controlled Trial

TypeinterventionalSponsorAzienda Ospedaliera Universitaria Integrata VeronaRan2020 to 2025Enrolled204ConditionsPostoperative Ileus, Postoperative Complications, Bowel Dysfunction, Pancreatic DiseasesArmsStandard coffee, Caffeine-free coffee, Drinking water
NCT05796063 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery: Can G-POCUS Guidance in Clinical Management of Gastrointestinal Recovery Lead to Better Outcomes?

TypeinterventionalSponsorThomas Jefferson UniversityRan2023 to 2024Enrolled128ConditionsIleus Postoperative, Postoperative Nausea and VomitingArmsgastric point of care ultrasound
NCT07182097 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Intraoperative Fentanyl vs. Remifentanil on Postoperative Bowel Function and Pain Outcomes in Laparoscopic Cholecystectomy: A Randomized Controlled Trial

TypeinterventionalSponsorKonya City HospitalRan2025 to 2026Enrolled106ConditionsPostoperative Bowel Function, Postoperative PainArmsFentanyl 2 µg/kg IV bolus + 1-2 µg/kg/h infusion during anesthesia, Remifentanil 1 µg/kg IV bolus + 0.1-1 µg/kg/min infusion during anesthesia
NCT07713472 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Benefits of Abdominal Massage After Colon Surgery for Cancer Following an ERAS Protocol (MATRAC_Ter): a Multicenter, Prospective, Randomized Clinical Trial

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2026 to 2028Enrolled225ConditionsColonic CancerArmsABDOMINAL MASSAGE, Usual physiotherapeutic intervention
3 · Its place in the literature

Who cites it

256 citing papers in PubMed, 20 syntheses or guidelines pooled it, 503 citations in OpenAlex.

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  7. Postoperative nutritional support after pancreaticoduodenectomy in adults.The Cochrane database of systematic reviews · 2025
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  9. Early versus delayed oral feeding after major gynaecologic surgery.The Cochrane database of systematic reviews · 2024
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  10. Enhanced recovery after surgery protocols following emergency intra-abdominal surgery: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
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  15. The Impact of Sham Feeding with Chewing Gum on Postoperative Ileus Following Colorectal Surgery: a Meta-Analysis of Randomised Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
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196 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ryash VatherDepartment of Surgery, University of Auckland, Auckland, New Zealand.
Sid Trivedi
Ian Bissett
University of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a lack of an internationally accepted standardised clinical definition for postoperative ileus (POI). This has made it difficult to estimate incidence and identify risk factors and has compromised external validity of clinical trials.

aimTo clarify terminology of POI and propose concise, clinically quantifiable definitions.

methodsA systematic review extracted definitions from randomised trials published between 1996 and 2011 investigating POI after abdominal surgery. This was followed by a global survey seeking opinions of those who have published in the field.

resultsDefinitions were extracted from 52 identified trials. Responses were received in the survey from 45 of 118 corresponding authors. Data were amalgamated to synthesise the following definitions: postoperative ileus (POI) "interval from surgery until passage of flatus/stool AND tolerance of an oral diet"; prolonged POI "two or more of nausea/vomiting, inability to tolerate oral diet over 24 h, absence of flatus over 24 h, distension, radiologic confirmation occurring on or after day 4 postoperatively without prior resolution of POI"; recurrent POI "two or more of nausea/vomiting, inability to tolerate oral diet over 24 h, absence of flatus over 24 h, distension, radiologic confirmation, occurring after apparent resolution of POI". Concordance of the latter two definitions with survey responses were ≥75 %.

conclusionWe have proposed standardised endpoints for use in future studies to facilitate objective comparison of competing interventions.

Indexed as

HumansIleusPostoperative ComplicationsRandomized Controlled Trials as TopicRisk FactorsTerminology as Topic

Identifiers

PMID23377782
OpenAlexW1980721253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.