ArticleEuropean radiology2013
Prostate cancer recurrence after radical prostatectomy: the role of 3-T diffusion imaging in multi-parametric magnetic resonance imaging.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Functional Magnetic Resonance Imaging in the Diagnosis of Locally Recurrent Prostate Cancer: Are All Pulse Sequences Helpful?Korean journal of radiologyPooled it
- Whole-body diffusion-weighted magnetic resonance imaging (WB-DW-MRI) vs choline-positron emission tomography-computed tomography (choline-PET/CT) for selecting treatments in recurrent prostate cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2017Trial
- Interpreting Prostate Multiparametric MRI: Beyond Adenocarcinoma - Anatomical Variations, Mimickers, and Post-Intervention Changes.Seminars in ultrasound, CT, and MR · 2025Review
- An MRI assessment of prostate cancer local recurrence using the PI-RR system: diagnostic accuracy, inter-observer reliability among readers with variable experience, and correlation with PSA values.European radiology · 2024Article
- Review
- Hybrid magnetic resonance and PET imaging for prostate cancer recurrence.Current opinion in oncology · 2023Review
- Role of magnetic resonance imaging for preoperative prediction of early biochemical failure in localized prostate cancer.Quantitative imaging in medicine and surgery · 2023Article
- Article
- Diagnostic yield of multiparametric MRI for local recurrence at biochemical recurrence after radical prostatectomy.Prostate international · 2022Article
- The role of MRI in prostate cancer: current and future directions.Magma (New York, N.Y.) · 2022Review
- Article
- Article
- Targeting Local Recurrence After Surgery With MRI Imaging for Prostate Cancer in the Setting of Salvage Radiation Therapy.Frontiers in oncology · 2022Review
- Detecting recurrent prostate Cancer using multiparametric MRI, influence of PSA and Gleason grade.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021Article
- Radiation Therapy After Radical Prostatectomy: What Has Changed Over Time?Frontiers in surgery · 2021Review
- Arguments against using an abbreviated or biparametric prostate MRI protocol.Abdominal radiology (New York) · 2020Review
- Sensitivity of CE-MRI in detecting local recurrence after radical prostatectomy.La Radiologia medica · 2020Article
- Salvage therapy at biochemical recurrence of prostate cancer.Nature reviews. Urology · 2020Article
- MR-Guided Radiotherapy for Prostate Cancer.Frontiers in oncology · 2020Review
- Macroscopic locoregional relapse from prostate cancer: which role for salvage radiotherapy?Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019Article
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8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo validate the role of 3-T diffusion-weighted imaging (DWI) in the detection of local prostate cancer recurrence after radical prostatectomy (RP).
methodsT2-weighted imaging, DWI and dynamic contrast-enhanced MRI (DCE-MRI) were performed with a 3-T magnet in 262 patients after RP. Twenty out of 262 patients evaluated were excluded. MRI results were validated by prostate-specific antigen (PSA) reduction after external beam radiotherapy in group A (126 patients, local recurrence size range 4-8 mm) and by transrectal ultrasound biopsy in group B (116 patients, local recurrence size range 9-15 mm).
resultsIn group A combined T2-weighted and DCE-MRI (T2+DCE) shows 98 % sensitivity, 94 % specificity and 93 % accuracy in identifying local recurrence; combined T2-weighted and DWI with a b value of 3,000 s/mm(2) (T2+DW3) displays 97 % sensitivity, 95 % specificity and 92 % accuracy, while with a b value of 1,000 s/mm(2) (T2+DW1) affords 93 % sensitivity, 89 % specificity and 88 % accuracy. In group B T2+DCE shows 100 % sensitivity, 97 % specificity and 91 % accuracy in detecting local cancer recurrence; T2+DW3 displays 98 % sensitivity, 96 % specificity and 89 % accuracy; T2+DW1 has 94 % sensitivity, 92 % specificity and 86 % accuracy.
conclusionDCE-MRI is the most reliable technique in detecting local prostate cancer recurrence after RP, though DWI can be proposed as a reliable alternative. KEY POINTS: • Diffusion-weighted magnetic resonance imaging (DWI-MRI) is being increasingly used in oncology. • PSA analysis does not distinguish prostate cancer recurrence from distant metastasis. • DWI-MR can diagnose local prostate cancer recurrence after radical prostatectomy. • DWI-MR is almost comparable to DCE-MRI in detecting local recurrence.
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