Evidence map›Paper›PMID 23377024›Full record

Trial reportPsychopharmacology2013

Effects of caffeine and alcohol on mood and performance changes following consumption of lager.

Andrew P Smith

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Psychopharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. The Effects of Caffeine on Anxiety Behavior in Healthy Individuals: A Systematic Review of the Literature.Stress and health : journal of the International Society for the Investigation of Stress · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Within-day associations between affect and intentions to drink alcohol in adolescents and young adults: A registered report.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  6. Review
  7. Article
  8. Adenosine AScientific reports · 2017
    Article
  9. Article
  10. Desire to Drink Alcohol is Enhanced with High Caffeine Energy Drink Mixers.Alcoholism, clinical and experimental research · 2016
    Article
  11. Can energy drinks increase the desire for more alcohol?Advances in nutrition (Bethesda, Md.) · 2015
    Review
  12. Review
  13. Review
  14. Caffeinated Alcoholic Beverages - An Emerging Trend in Alcohol Abuse.Journal of addiction research & therapy · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Andrew P SmithCentre for Occupational and Health Psychology, School of Psychology, Cardiff University, 63 Park Place, Cardiff, CF10 3AS, UK. smithap@cardiff.ac.uk
Cardiff University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleThe present study examined whether caffeine would modify the behavioural effects of alcohol.

objectivesThe aim of the study was to determine whether caffeine modifies the effects of alcohol on mood and psychomotor performance and to identify possible dose-response and temporal relationships.

methodsA double-blind study examined the effects of three successive lager drinks (330 ml each) in the early afternoon on mood and psychomotor performance assessed at 30-min intervals over a 2-h period. Participants carried out a baseline session and were then randomly assigned to one of six conditions formed by combining three different doses of caffeine (0, 62.5 and 125 mg per drink) with either no alcohol or 4.3 % alcohol. One hundred and forty-six young adults (65 male, 81 female; age range 18-30 years) participated in the study. Mood (alertness, hedonic tone and anxiety) was assessed before and after performing simple reaction time and choice reaction time tasks.

resultsAlcohol was associated with higher hedonic tone (p < 0.005), reduced anxiety (p < 0.05) and reduced alertness (p < 0.005). Caffeine had no modifying effect on hedonic tone or anxiety. However, the highest dose of caffeine did remove the effect of alcohol on alertness (p < 0.05). Effects of alcohol and caffeine were found on the performance tasks (all p values < 0.05) but these were independent effects.

conclusionsThe results from the present study confirm that caffeine does not remove the negative effects of alcohol on performance although high doses counteract the drop in subjective alertness produced by alcohol.

Indexed as

AdolescentAdultAffectAlcohol DrinkingCaffeineDose-Response Relationship, DrugDouble-Blind MethodDrug InteractionsEthanolFemaleHumansMalePsychomotor PerformanceReaction TimeYoung AdultCaffeineEthanol

Identifiers

PMID23377024
OpenAlexW2076301275

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.