Evidence map›Paper›PMID 23375943›Full record

ArticleSchizophrenia research2013

Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder.

Margaret M McClure, Philip D Harvey, Christopher R Bowie, Brian Iacoviello, Larry J Siever

Open access · greenAbstract readComparative Study
In one paragraph

Article in Schizophrenia research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 63 citations in OpenAlex.

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  19. Schizotypal personality disorder: a current review.Current psychiatry reports · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Margaret M McClureDepartment of Psychiatry, Mt. Sinai School of Medicine, New York, NY, United States. Margaret.McNamara@mssm.edu
Philip D Harvey
Christopher R Bowie
Brian Iacoviello
Larry J Siever
Fairfield University · USNew York/New Jersey VA Health Care Network · USQueen's University · CAUniversity of Miami · US

Funding

ZIPRASIDONE (GEODON) AUGMENTATION IN SEROTONIN REUPTAKE INHIBITOR-RESISTANT OBM01RR000071 · NCRR · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI NEWCORN, JEFFREY H · 1985 to 2009
$41.5M
Pharmacology of Cognition in Schizotypal Personality DisorderR01MH056140 · NIMH · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI SIEVER, LARRY J · 1997 to 2011
$4.0M
Validation of Measures of real-world outcomeR01MH078775 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI HARVEY, PHILIP D. · 2007 to 2011
$1.7M
NCRR NIH HHS M01 RR000071NCRR NIH HHS MO1-RR-00071NIMH NIH HHS MH 56140NIMH NIH HHS MH 78775NIMH NIH HHS R01 MH056140NIMH NIH HHS R01 MH078775
6 · The paper itself

Abstract

backgroundIndividuals with schizotypal personality disorder (SPD) exhibit impaired cognitive functioning in a pattern similar to that found in schizophrenia; less clear is the extent to which these individuals also share schizophrenia patients' impairments in functional capacity and real-world functioning.

methodWe evaluated 46 SPD patients, as well as 38 individuals with avoidant personality disorder (AvPD) and 55 healthy controls (HC) on: cognitive functioning, real-world functioning (employment and residential status), and functional capacity (indexed by the UPSA, a performance-based skills assessment).

resultsWe found that individuals with SPD exhibited worse performance on both the cognitive battery and the UPSA than the other groups; they were also less likely to be employed and to be living independently. Additionally, cognitive and UPSA performance in the SPD group was intercorrelated to a degree comparable to what has been found in schizophrenia, and this relationship was not present in the AvPD group. Finally, real-world functioning was related to UPSA performance for both patient groups.

conclusionsSPD patients exhibit impaired real-world functioning suggesting that these deficits extend across the schizophrenia spectrum. In addition, there is supportive evidence for the validity and importance of performance-based measures such as the UPSA to predict everyday outcomes across the schizophrenia spectrum.

Indexed as

Activities of Daily LivingAdultCognition DisordersCommunicationComprehensionEmploymentFemaleHumansMaleNeuropsychological TestsPersonality DisordersPsychiatric Status Rating ScalesSchizotypal Personality DisorderWechsler Scales

Identifiers

PMID23375943
PMCPMC3572293
OpenAlexW2068061645

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.