Trial reportPsychoneuroendocrinology2013
Reduction in salivary α-amylase levels following a mind-body intervention in cancer survivors--an exploratory study.
Trial report in Psychoneuroendocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- A Systematic Review of Circulatory microRNAs in Major Depressive Disorder: Potential Biomarkers for Disease Prognosis.International journal of molecular sciences · 2022Pooled it
- MicroRNAs expressed in depression and their associated pathways: A systematic review and a bioinformatics analysis.Journal of chemical neuroanatomy · 2019Pooled it
- Meditation and Cardiovascular Risk Reduction: A Scientific Statement From the American Heart Association.Journal of the American Heart Association · 2017Guideline
- Use of Salivary Diurnal Cortisol as an Outcome Measure in Randomised Controlled Trials: a Systematic Review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2016Pooled it
- Effectiveness of Mindfulness-Based Stress Reduction on Salivary Cortisol and α-amylase Level, Anxiety and Depression in Students: A Randomized and Parallel-Group Clinical Trial.Applied psychophysiology and biofeedback · 2025Trial
- The effect of mindfulness meditation on dental anxiety during implant surgery: a randomized controlled clinical trial.Scientific reports · 2023Trial
- Stress, subjective wellbeing and self-knowledge in higher education teachers: A pilot study through bodyfulness approaches.PloS one · 2022Trial
- The Effect of Clown Intervention on Self-Report and Biomarker Measures of Stress and Fatigue in Pediatric Osteosarcoma Inpatients: A Pilot Study.Integrative cancer therapies · 2018Trial
- Exploring the impact of chronotype, chrononutrition and lifestyle on bladder cancer.International urology and nephrology · 2025Article
- Nature-based interventions reduce physiological stress in children with chronic illnesses: evidence from salivary biomarkers.Frontiers in public health · 2025Article
- What can the psychoneuroimmunology of yoga teach us about depression's psychopathology?Brain, behavior, & immunity - health · 2024Article
- Article
- Trends in waking salivary alpha-amylase levels following healing lucid dreams.Frontiers in psychology · 2024Article
- Baseline states of mind differentially affected diurnal salivary stress biomarkers: A preliminary study.Heliyon · 2022Article
- Article
- Yoga, Meditation, Breathing Exercises, and Inflammatory Biomarkers with Possible Implications in COVID-19: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Four Weeks of a Neuro-Meditation Program Improves Sleep Quality and Reduces Hypertension in Nursing Staff During the COVID-19 Pandemic: A Parallel Randomized Controlled Trial.Frontiers in psychology · 2022Article
- Salivary Alpha-Amylase as a Biomarker of Stress in Behavioral Medicine.International journal of behavioral medicine · 2020Article
- Expert Opinion: Meditation and Cardiovascular Health: What is the Link?European cardiology · 2019Review
- Progression of intervention-focused research for Gulf War illness.Military Medical Research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe main aim of this exploratory study was to assess whether salivary α-amylase (sAA) and salivary cortisol levels would be positively modulated by sleep-focused mind-body interventions in female and male cancer survivors.
methodsWe conducted a randomized controlled trial in which 57 cancer survivors with self-reported sleep disturbance received either a Sleep Hygiene Education (SHE; n=18) control, or one of two experimental mind-body interventions, namely, Mind-Body Bridging (MBB; n=19) or Mindfulness Meditation (MM; n=20). Interventions were three sessions each conducted once per week for three consecutive weeks. Saliva cortisol and sAA were measured at baseline and 1 week after the last session. Participants also completed a sleep scale at the same time points when saliva was collected for biomarker measurement.
resultsOur study revealed that at post-intervention assessment, mean sAA levels upon awakening ("Waking" sample) declined in MBB compared with that of SHE. Mean Waking cortisol levels did not differ among treatment groups but declined slightly in SHE. Self-reported sleep improved across the three interventions at Post-assessment, with largest improvements in the MBB intervention.
conclusionIn this exploratory study, sleep focused mind-body intervention (MBB) attenuated Waking sAA levels, suggesting positive influences of a mind-body intervention on sympathetic activity in cancer survivors with sleep disturbance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.