Evidence map›Paper›PMID 23374739›Full record

ReviewJournal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Normocalcemic primary hyperparathyroidism.

Natalie E Cusano, Shonni J Silverberg, John P Bilezikian

Open access · greenAbstract readReview
In one paragraph

Review in Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 174 citations in OpenAlex.

  1. Spontaneous neck hematoma secondary to parathyroid adenoma: a case series.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
    Pooled it
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  4. Effects of alendronate and vitamin D in patients with normocalcemic primary hyperparathyroidism.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2015
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Natalie E CusanoDivision of Endocrinology, Department of Medicine, College of Physicians & Surgeons, Columbia University, New York, NY 10032, USA.
Shonni J Silverberg
John P Bilezikian
Columbia University · US

Funding

PRIMARY HYPERPARATHYROIDISMR01DK032333 · NIDDK · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI BILEZIKIAN, JOHN P · 1986 to 2018
$9.6M
Vitamin D Deficiency in Primary HyperparathyroidismR01DK084986 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SILVERBERG, SHONNI J · 2010 to 2014
$3.0M
Non-Classical Manifestations of Primary HyperparathyroidismK24DK074457 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SILVERBERG, SHONNI J · 2006 to 2016
$1.7M
Skeletal Regulation of Cortical and Trabecular Bone by Parathyroid HormoneK23DK095944 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CUSANO, NATALIE · 2012 to 2016
$918k
NIDDK NIH HHS K23 DK095944NIDDK NIH HHS K24 DK074457NIDDK NIH HHS R01 DK032333NIDDK NIH HHS R01 DK084986
6 · The paper itself

Abstract

Primary hyperparathyroidism, a common endocrine disorder, is traditionally defined by hypercalcemia and elevated levels of parathyroid hormone (PTH). A newer presentation of primary hyperparathyroidism has been described over the past decade, in which PTH is elevated but serum calcium is consistently normal, in the absence of secondary causes of hyperparathyroidism, such as renal disease or vitamin D deficiency. Recognition of this phenotype of primary hyperparathyroidism, normocalcemic primary hyperparathyroidism, supports a biphasic chronological time course in some individuals in which PTH levels are first elevated but serum calcium is normal, followed by the development of frank hypercalcemia. This review focuses on the available literature regarding this newly described phenotype of primary hyperparathyroidism.

Indexed as

CalciumHumansHyperparathyroidism, PrimaryParathyroid HormonePhenotypeVitamin D DeficiencyCalciumParathyroid Hormone

Identifiers

PMID23374739
PMCPMC3564219
OpenAlexW2082237792

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.