ArticleMayo Clinic proceedings2013
Increasing incidence of nutritional rickets: a population-based study in Olmsted County, Minnesota.
Article in Mayo Clinic proceedings, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.
- Serum 25-hydroxyvitamin D threshold and risk of rickets in young children: a systematic review and individual participant data meta-analysis to inform the development of dietary requirements for vitamin D.European journal of nutrition · 2024Pooled it
- Maternal vitamin D supplementation to improve the vitamin D status of breast-fed infants: a randomized controlled trial.Mayo Clinic proceedings · 2013Trial
- Long-term epidemiological insights into rickets: a nationwide population-based retrospective study.Clinical and experimental pediatrics · 2025Article
- Does rickets carry an increased risk of osteomyelitis and septic arthritis? An aggregated electronic health record data study.Journal of pediatric orthopedics. Part B · 2025Article
- Dental Manifestations in Children Affected by Hypophosphatemic Rickets: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Vitamin D and pediatric bone health: Important information and considerations for the pediatric orthopaedic surgeon.Journal of the Pediatric Orthopaedic Society of North America · 2024Article
- Article
- The impact of metabolic disorders on management of periodontal health in children.Pediatric discovery · 2024Article
- Vitamin D testing in children and adolescents in Victoria, Australia: are testing practices in line with global recommendations?Archives of disease in childhood · 2023Article
- Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement.The Journal of clinical endocrinology and metabolism · 2023Article
- Bone turnover profile and muscular status in major orthopaedic surgery: a case series.Acta bio-medica : Atenei Parmensis · 2023Article
- Nutritional Rickets Among Children: A Retrospective Study from Saudi Arabia.Pediatric health, medicine and therapeutics · 2023Article
- Establishing the Prevalence of Osteomalacia in Arab Adolescents Using Biochemical Markers of Bone Health.Nutrients · 2022Article
- Orthopedic manifestations of child abuse.Pediatric research · 2022Review
- Normocephalic sagittal craniosynostosis in young children is common and unrecognized.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Vitamin D Intake and Meeting Recommendations Among Infants Participating in WIC Nationally.Journal of nutrition education and behavior · 2022Article
- Dairy as a Source of Iodine and Protein in the UK: Implications for Human Health Across the Life Course, and Future Policy and Research.Frontiers in nutrition · 2022Review
- Trends in Vitamin D Status Around the World.JBMR plus · 2021Article
- Rickets in Children: An Update.Biomedicines · 2021Review
- Rickets manifestations in a child with metaphyseal anadysplasia, report of a spontaneously resolving case.BMC pediatrics · 2021Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveTo determine temporal trends in incidence and risk factors of nutritional rickets in a community-based population. PATIENTS AND
methodsRochester Epidemiology Project data were used to identify all children (aged <18 years) residing in Olmsted County, Minnesota, between January 1, 1970, and December 31, 2009, with diagnostic codes corresponding to rickets, vitamin D deficiency, hypovitaminosis D, rachitis, osteomalacia, genu varum, genu valgum, craniotabes, hypocalcemia, hypocalcemic seizure, and tetany. Record abstraction was performed to select individuals with radiographic confirmation of rickets. Age- and sex-matched controls were identified for the evaluation of risk factors. The main outcome measure was radiographic evidence of rickets without identifiable inherited, genetic, or nonnutritional causes. Incidence rates were calculated using Rochester Epidemiology Project census data.
resultsOf 768 children with eligible diagnostic codes, 23 had radiographic evidence of rickets; of these, 17 children had nutritional rickets. All 17 children were younger than 3 years, and 13 (76%) were of nonwhite race/ethnicity. Clinical presentation included poor growth (n=12), leg deformity (n=8), motor delay (n=5), leg pain (n=3), weakness (n=3), and hypocalcemia or tetany (n=2). The incidence of nutritional rickets in children younger than 3 years was 0, 2.2, 3.7, and 24.1 per 100,000 for the decades beginning in 1970, 1980, 1990, and 2000, respectively (P=.003 for incidence trend). Nutritional rickets was associated with black race, breast-feeding, low birth weight, and stunted growth (P<.05 for all). Four of 13 patients (31%) who underwent 25-hydroxyvitamin D testing had values less than 10 ng/mL.
conclusionNutritional rickets remains rare, but its incidence has dramatically increased since 2000. Not all cases of rickets can be attributed to vitamin D deficiency.
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