ReviewEpidemiologic reviews2013
The epidemiology of longevity and exceptional survival.
Review in Epidemiologic reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 3 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence.Nature genetics · 2017Pooled it
- Limitations and risks of meta-analyses of longevity studies.Mechanisms of ageing and development · 2017Pooled it
- The transcriptional landscape of age in human peripheral blood.Nature communications · 2015Pooled it
- A multistate model of health transitions in older people: a secondary analysis of ASPREE clinical trial data.The lancet. Healthy longevity · 2022Trial
- Is my loneliness killing me? Effects of loneliness and social isolation on transitions between cognitive status categories and death.Journal of personality and social psychology · 2026Article
- Developmental origins of exceptional health and survival: a four-generation family cohort study.Nature communications · 2026Article
- Aging-Induced QT Prolongation as a Potential Contributor to Longevity.Journal of cardiovascular development and disease · 2026Review
- A Multicohort Machine Learning Framework to Predict Mortality in Elderly Patients With Heart Disease: Insights From HARLS, SHARE, and HRS.Cardiovascular therapeutics · 2026Article
- Advances in the Study of Protein Deamidation: Unveiling Its Influence on Aging, Disease Progression, Forensics and Therapeutic Efficacy.Proteomes · 2025Review
- Mortality Trends in Pre-COVID-19 and COVID-19 Eras Among Oldest Veterans.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- Dynamic changes in gene expression through aging in Drosophila melanogaster heads.G3 (Bethesda, Md.) · 2025Article
- Functional outcomes following injury in centenarians: a nationwide retrospective observational study.World journal of emergency surgery : WJES · 2025Observational
- Factors involved in human healthy aging: insights from longevity individuals.Frontiers of medicine · 2025Review
- Living longer and lifestyle: A report on the oldest of the old in the Adventist Health Study-2.JAR life · 2025Article
- Dynamic Changes in Gene Expression Through Aging inbioRxiv : the preprint server for biology · 2024Article
- Methylation entropy landscape of Chinese long-lived individuals reveals lower epigenetic noise related to human healthy aging.Aging cell · 2024Article
- Plasma proteomic signature of human longevity.Aging cell · 2024Article
- The association of leukocyte telomere length with exceptional longevity among older women.GeroScience · 2024Article
- Defining familial longevity and developing a familial longevity score for unbiased epigenetic studies in a birth cohort.Epigenomics · 2024Article
- Scrutiny of genome-wide somatic mutation profiles in centenarians identifies the key genomic regions for human longevity.Aging cell · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The field of the "epidemiology of longevity" has been expanding rapidly in recent years. Several long-term cohort studies have followed older adults long enough to identify the most long-lived and to define many factors that lead to a long life span. Very long-lived people such as centenarians have been examined using case-control study designs. Both cohort and case-control studies have been the subject of genome-wide association studies that have identified genetic variants associated with longevity. With growing recognition of the importance of rare variations, family studies of longevity will be useful. Most recently, exome and whole-genome sequencing, gene expression, and epigenetic studies have been undertaken to better define functional variation and regulation of the genome. In this review, we consider how these studies are leading to a deeper understanding of the underlying biologic pathways to longevity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.