ArticleThe Plant cell2013
A developmental framework for complex plasmodesmata formation revealed by large-scale imaging of the Arabidopsis leaf epidermis.
Article in The Plant cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Role of Plasmodesmata During Plant-Pathogen Interactions.The plant pathology journal · 2026Review
- Quantification of cell-type-specific plasmodesmata distribution in Arabidopsis roots reveals spatial and patterning dynamics.The Plant journal : for cell and molecular biology · 2026Article
- Abscisic acid signaling regulates primary plasmodesmata density for plant cell-to-cell communication.Science advances · 2025Article
- The Hemibiotrophic Apple Scab FungusJournal of fungi (Basel, Switzerland) · 2024Article
- Article
- Multicellularity and the Need for Communication-A Systematic Overview on (Algal) Plasmodesmata and Other Types of Symplasmic Cell Connections.Plants (Basel, Switzerland) · 2023Review
- Focused Ion Beam-Scanning Electron Microscopy for Investigating Plasmodesmal Densities.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Leaf-size control beyond transcription factors: Compensatory mechanisms.Frontiers in plant science · 2022Review
- Investigating Plasmodesmata Function in Arabidopsis Thaliana Using a Low-Pressure Bombardment System and GFP Movement Assay.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Function of Plasmodesmata in the Interaction of Plants with Microbes and Viruses.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Guard cells control hypocotyl elongation through HXK1, HY5, and PIF4.Communications biology · 2021Article
- Intercellular trafficking via plasmodesmata: molecular layers of complexity.Cellular and molecular life sciences : CMLS · 2021Review
- Leaf Epidermis: The Ambiguous Symplastic Domain.Frontiers in plant science · 2021Article
- A Sight on Single-Cell Transcriptomics in Plants Through the Prism of Cell-Based Computational Modeling Approaches: Benefits and Challenges for Data Analysis.Frontiers in genetics · 2021Review
- Computational Tools for Serial Block Electron Microscopy Reveal Plasmodesmata Distributions and Wall Environments.Plant physiology · 2020Article
- Chloroplast-to-nucleus retrograde signalling controls intercellular trafficking via plasmodesmata formation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- From plasmodesma geometry to effective symplasmic permeability through biophysical modelling.eLife · 2019Article
- The Coumarin Glucoside, Esculin, Reveals Rapid Changes in Phloem-Transport Velocity in Response to Environmental Cues.Plant physiology · 2018Article
- Symplasmic Intercellular Communication through Plasmodesmata.Plants (Basel, Switzerland) · 2018Article
- A Salutary Role of Reactive Oxygen Species in Intercellular Tunnel-Mediated Communication.Frontiers in cell and developmental biology · 2018Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Plasmodesmata (PD) form tubular connections that function as intercellular communication channels. They are essential for transporting nutrients and for coordinating development. During cytokinesis, simple PDs are inserted into the developing cell plate, while during wall extension, more complex (branched) forms of PD are laid down. We show that complex PDs are derived from existing simple PDs in a pattern that is accelerated when leaves undergo the sink-source transition. Complex PDs are inserted initially at the three-way junctions between epidermal cells but develop most rapidly in the anisocytic complexes around stomata. For a quantitative analysis of complex PD formation, we established a high-throughput imaging platform and constructed PDQUANT, a custom algorithm that detected cell boundaries and PD numbers in different wall faces. For anticlinal walls, the number of complex PDs increased with increasing cell size, while for periclinal walls, the number of PDs decreased. Complex PD insertion was accelerated by up to threefold in response to salicylic acid treatment and challenges with mannitol. In a single 30-min run, we could derive data for up to 11k PDs from 3k epidermal cells. This facile approach opens the door to a large-scale analysis of the endogenous and exogenous factors that influence PD formation.
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Registered trials
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