Evidence map›Paper›PMID 23371801›Full record

ArticleChembiochem : a European journal of chemical biology2013

Selective fluorogenic chemosensors for distinct classes of nucleases.

Jong-Wha Jung, Sarah K Edwards, Eric T Kool

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Fluorescent Probes of DNA Repair.ACS chemical biology · 2018
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jong-Wha JungCollege of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, 702-701, Korea.
Sarah K Edwards
Eric T Kool

Funding

Probing Nucleotide Recognition in the Genetic Information PathwayR01GM072705 · NIGMS · STANFORD UNIVERSITY · PI KOOL, ERIC T. · 2004 to 2012
$2.4M
POLYFLUOROPHORES ASSEMBLED ON A DNA SCAFFOLDR01GM067201 · NIGMS · STANFORD UNIVERSITY · PI KOOL, ERIC T. · 2003 to 2011
$2.2M
NIGMS NIH HHS GM067201NIGMS NIH HHS GM072705NIGMS NIH HHS R01 GM067201NIGMS NIH HHS R01 GM072705
6 · The paper itself

Abstract

nuclease sensor trioFluorogenic DNA sensors were developed for distinct classes of nucleases: 3'-exonucleases, 5'-exonucleases, and endonucleases. The highly selective sensors, built from very small modified DNA oligomers containing the unnatural fluorescent base pyrene, and employing thymine as a quencher, were found to function in a variety of complex biological media.

Indexed as

Biosensing TechniquesDNAEndonucleasesExonucleasesFluorescent DyesHeLa CellsHumansOligonucleotidesPyrenesStaphylococcusDNAEndonucleasesExonucleasesFluorescent DyesOligonucleotidespyrenePyrenes

Identifiers

PMID23371801
PMCPMC3770146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.