Evidence map›Paper›PMID 23370859›Full record

Trial reportEuropean journal of applied physiology2013

Dietary nitrate supplementation improves team sport-specific intense intermittent exercise performance.

Lee J Wylie, Magni Mohr, Peter Krustrup, Sarah R Jackman, Georgios Ermιdis, James Kelly, Matthew I Black, Stephen J Bailey, Anni Vanhatalo, Andrew M Jones

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 95 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02436629 phase4completednot on this mapstarted 2015, after this paper: background citation

The Effect of Nitrate Supplementation on Sport Performance: High Intensity Intermittent Performance in Recreational Athletes

TypeinterventionalSponsorMaastricht University Medical CenterRan2015 to 2016Enrolled40ConditionsHigh Intensity Intermittent Sports PerformanceArmsNitrate-rich concentrated beetroot juice, Nitrate-depleted concentrated red beetroot juice
NCT02850367 nacompletednot on this mapstarted 2016, after this paper: background citation

The Effect of NO Precursors on Physiological Responses to Exercise

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2016 to 2021Enrolled63ConditionsPhysiologyArmsNitrate, Nitrate and L-Arginine, Nitrate and L-Citrulline, Placebo, Evaluation of post-ischemic vascular reactivity
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 10 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Trial
  19. Trial
  20. Trial

35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lee J WylieSport and Health Sciences, College of Life and Environmental Sciences, University of Exeter, St. Luke's Campus, Heavitree Road, Exeter EX1 2LU, UK.
Magni Mohr
Peter Krustrup
Sarah R Jackman
Georgios Ermιdis
James Kelly
Matthew I Black
Stephen J Bailey
Anni Vanhatalo
Andrew M Jones

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have suggested that dietary inorganic nitrate (NO₃(-)) supplementation may improve muscle efficiency and endurance exercise tolerance but possible effects during team sport-specific intense intermittent exercise have not been examined. We hypothesized that NO₃(-) supplementation would enhance high-intensity intermittent exercise performance. Fourteen male recreational team-sport players were assigned in a double-blind, randomized, crossover design to consume 490 mL of concentrated, nitrate-rich beetroot juice (BR) and nitrate-depleted placebo juice (PL) over ~30 h preceding the completion of a Yo-Yo intermittent recovery level 1 test (Yo-Yo IR1). Resting plasma nitrite concentration ([NO₂(-)]) was ~400% greater in BR compared to PL. Plasma [NO₂(-)] declined by 20% in PL (P < 0.05) and by 54 % in BR (P < 0.05) from pre-exercise to end-exercise. Performance in the Yo-Yo IR1 was 4.2% greater (P < 0.05) with BR (1,704 ± 304 m) compared to PL (1,636 ± 288 m). Blood [lactate] was not different between BR and PL, but the mean blood [glucose] was lower (3.8 ± 0.8 vs. 4.2 ± 1.1 mM, P < 0.05) and the rise in plasma [K(+)] tended to be reduced in BR compared to PL (P = 0.08). These findings suggest that NO₃(-) supplementation may promote NO production via the nitrate-nitrite-NO pathway and enhance Yo-Yo IR1 test performance, perhaps by facilitating greater muscle glucose uptake or by better maintaining muscle excitability. Dietary NO₃(-) supplementation improves performance during intense intermittent exercise and may be a useful ergogenic aid for team sports players.

Indexed as

Athletic PerformanceDietary SupplementsExerciseBeta vulgarisBeveragesBlood GlucoseDouble-Blind MethodHumansMaleNitratesNitritesPotassiumYoung AdultBlood GlucoseNitratesNitritesPotassium

Identifiers

PMID23370859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.