Evidence map›Paper›PMID 23370835›Full record

Trial reportAIDS and behavior2013

Impact of protein supplementation and care and support on body composition and CD4 count among HIV-infected women living in rural India: results from a randomized pilot clinical trial.

Adeline Nyamathi, Sanjeev Sinha, Kalyan K Ganguly, Padma Ramakrishna, P Suresh, Catherine L Carpenter

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00860769 (ASHA HIV Health Promotion Intervention in India), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00860769 phase1 / phase2completednot on this map

ASHA HIV Health Promotion Intervention in India

TypeinterventionalSponsorUniversity of California, Los AngelesRan2008 to 2012Enrolled68ConditionsHIV InfectionsArmsASHA LIFE, USUAL Care
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  14. Nutrition Care Model for Nutritional Assessment and Dietary Counseling of Adults Living with HIV in India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Adeline NyamathiSchool of Nursing, University of California at Los Angeles, Room 2-250, Factor Building, Los Angeles, CA 90095-1702, USA. anyamath@sonnet.ucla.edu
Sanjeev Sinha
Kalyan K Ganguly
Padma Ramakrishna
P Suresh
Catherine L Carpenter
University of California, Los Angeles · USAll India Institute of Medical Sciences · INIndian Council of Medical Research · IN

Funding

Vulnerable Populations/Health Disparities ResearchT32NR007077 · NINR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HODGE, FELICIA SCHANCHE · 1994 to 2016
$2.9M
ASHA HIV Health Promotion Intervention in IndiaR34MH082662 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NYAMATHI, ADELINE M · 2008 to 2010
$612k
NIMH NIH HHS MH82662NIMH NIH HHS R34 MH082662NINR NIH HHS T32 NR007077
6 · The paper itself

Abstract

Body composition in HIV-infected individuals is subject to many influences. We conducted a pilot 6-month randomized trial of 68 women living with AIDS (WLA) from rural India. High protein intervention combined with education and supportive care delivered by HIV-trained village women (activated social health activist [Asha] life [AL]) was compared to standard protein with usual care delivered by village community assistants (usual care [UC]). Measurements included CD4 counts, ART adherence, socio-demographics, disease characteristics (questionnaires); and anthropometry (bioimpedance analyzer). Repeated measures analysis of variance modeled associations. AL significantly gained in BMI, muscle mass, fat mass, ART adherence, and CD4 counts compared to UC, with higher weight and muscle mass gains among ART adherent (≥66%) participants who had healthier immunity (CD4 ≥450). BMI of WLA improved through high protein supplementation combined with education and supportive care. Future research is needed to determine which intervention aspect was most responsible.

Indexed as

CD4 Lymphocyte CountAdultAnti-HIV AgentsBody CompositionDepressionDietary ProteinsDietary SupplementsFemaleFood SupplyHIV InfectionsHumansIndiaMedication AdherencePatient Education as TopicPilot ProjectsRural PopulationAnti-HIV AgentsDietary Proteins

Identifiers

PMID23370835
PMCPMC3755868
OpenAlexW1977063222

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.