ArticleAJNR. American journal of neuroradiology2013
DTI values in key white matter tracts from infancy through adolescence.
Article in AJNR. American journal of neuroradiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 50 citations in OpenAlex.
- Prenatal substance exposure and infant neurodevelopment: a review of magnetic resonance imaging studies.Frontiers in human neuroscience · 2025Review
- Gray matter based spatial statistics framework in the 1-month brain: insights into gray matter microstructure in infancy.Brain structure & function · 2024Article
- Abnormality of Early White Matter Development in Tuberous Sclerosis Complex and Autism Spectrum Disorder: Longitudinal Analysis of Diffusion Tensor Imaging Measures.Journal of child neurology · 2024Article
- Cerebellar peduncle damage in Langerhans cell histiocytosis-associated neurodegenerative disease revealed by diffusion tensor imaging.Neuroradiology · 2024Article
- Reduced white matter maturation in the central auditory system of children living with HIV.Frontiers in neuroimaging · 2024Article
- White matter tract microstructure, macrostructure, and associated cortical gray matter morphology across the lifespan.bioRxiv : the preprint server for biology · 2023Article
- White matter tract microstructure, macrostructure, and associated cortical gray matter morphology across the lifespan.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- Translating ENIGMA schizophrenia findings using the regional vulnerability index: Association with cognition, symptoms, and disease trajectory.Human brain mapping · 2022Article
- Assessing early erythrolysis and the relationship to perihematomal iron overload and white matter survival in human intracerebral hemorrhage.CNS neuroscience & therapeutics · 2021Article
- Altered Thalamocortical Connectivity in 6-Week-Old Infants at High Familial Risk for Autism Spectrum Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Brain White Matter Abnormality Induced by Chronic Spinal Cord Injury in the Pediatric Population: A Preliminary Tract-based Spatial Statistic Study.Topics in spinal cord injury rehabilitation · 2021Article
- Assessing changes in microstructural integrity of white matter tracts in children with leukaemia following exposure to chemotherapy.Pediatric radiology · 2020Article
- Magnitude and timing of major white matter tract maturation from infancy through adolescence with NODDI.NeuroImage · 2020Article
- Abnormal anisotropic diffusion properties in pediatric myelomeningocele patients treated with fetal surgery: an initial DTI study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Article
- Asymmetric Insular Connectomics Revealed by Diffusion Magnetic Resonance Imaging Analysis of Healthy Brain Development.Brain connectivity · 2019Article
- Age-Related Alterations of White Matter Integrity in Adolescents and Young Adults With Bipolar Disorder.Frontiers in psychiatry · 2019Article
- Excitatory Repetitive Transcranial Magnetic Stimulation Induces Contralesional Cortico-Cerebellar Pathways After Acute Ischemic Stroke: A Preliminary DTI Study.Frontiers in behavioral neuroscience · 2018Article
- Age related diffusion and tractography changes in typically developing pediatric cervical and thoracic spinal cord.NeuroImage. Clinical · 2018Article
- Oxidative stress, prefrontal cortex hypomyelination and cognitive symptoms in schizophrenia.Translational psychiatry · 2017Review
- Development of cortical motor circuits between childhood and adulthood: A navigated TMS-HdEEG study.Human brain mapping · 2017Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
background and purposeDTI is an advanced neuroimaging technique that allows in vivo quantification of water diffusion properties as surrogate markers of the integrity of WM microstructure. In our study, we investigated normative data from a large number of pediatric and adolescent participants to examine the developmental trends in DTI during this conspicuous WM maturation period. MATERIALS AND
methodsDTI data in 202 healthy pediatric and adolescent participants were analyzed retrospectively. Fractional anisotropy and mean diffusivity values in the corpus callosum and internal capsule were fitted to an exponential regression model to delineate age-dependent maturational changes across the WM structures.
resultsThe DTI metrics demonstrated characteristic exponential patterns of progression during development and conspicuous age-dependent changes in the first 36 months, with rostral WM tracts experiencing the highest slope of the exponential function. In contrast, the highest final FA and lowest MD values were detected in the splenium of the corpus callosum and the posterior limb of the internal capsule.
conclusionsOur analysis shows that the more caudal portions of the corpus callosum and internal capsule begin the maturation process earlier than the rostral regions, but the rostral regions develop at a more accelerated pace, which may suggest that rostral regions rely on development of more caudal brain regions to instigate their development. Our normative DTI can be used as a reference to study normal spatiotemporal developmental profiles in the WM and help identify abnormal WM structures in patient populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.