Evidence map›Paper›PMID 23370333›Full record

ReviewCancer gene therapy2013

The innovative evolution of cancer gene and cellular therapies.

P Lam, G Khan, R Stripecke, K M Hui, N Kasahara, K-W Peng, B-A Guinn

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer gene therapy, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Step-by-Step Immune Activation for Suicide Gene Therapy Reinforcement.International journal of molecular sciences · 2021
    Review
  3. Article
  4. Role of Recombinant DNA Technology to Improve Life.International journal of genomics · 2016
    Review
  5. Article
  6. Article
  7. Gene therapy on the move.EMBO molecular medicine · 2013
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P LamDivision of Cellular and Molecular Research, National Cancer Centre, Singapore, Singapore.
G Khan
R Stripecke
K M Hui
N Kasahara
K-W Peng
B-A Guinn

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We provide an overview of the latest developments in cancer gene therapy--from the bench to early-stage clinical trials. We describe the most recent work of worldwide teams including experienced scientists and clinicians, reflecting the recent emergence of gene therapy from the 'Valley of Death'. The treatment efficacy of clinical gene therapy has now been shown in a number of diseases including cancer and we are observing a renewed interest by big pharmaceutical and biotechnology companies most obviously demonstrated by Amgen's acquisition of Biovex for up to USD$1 billion. There is an opportunity to be cautiously hopeful regarding the future of gene therapy in the clinic and we review here some of the most recent progress in the field.

Indexed as

Cell- and Tissue-Based TherapyGenetic TherapyAnimalsBiomarkers, TumorClinical Trials, Phase I as TopicClinical Trials, Phase II as TopicGenetic VectorsGene Transfer TechniquesHumansImmunotherapyMolecular Targeted TherapyNeoplasmsPrecision MedicineRNA InterferenceBiomarkers, Tumor

Identifiers

PMID23370333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.