ArticleThe Journal of urology2013
Antibiotic resistance patterns of outpatient pediatric urinary tract infections.
Article in The Journal of urology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 2 of them syntheses that pooled it.
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Who cites it
82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 227 citations in OpenAlex.
- Global prevalence and etiologies of urinary tract infection among oncologic patients: a systematic review and meta-analysis.World journal of urology · 2025Pooled it
- Global prevalence of antibiotic resistance in paediatric urinary tract infections caused by Escherichia coli and association with routine use of antibiotics in primary care: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2016Pooled it
- The influence of antibiotic prophylaxis on bacterial resistance in urinary tract infections in children with spina bifida.BMC infectious diseases · 2017Trial
- Predictors of Antimicrobial Resistance among Pathogens Causing Urinary Tract Infection in Children.The Journal of pediatrics · 2016Trial
- Urinary tract infections in children.Nature reviews. Urology · 2026Review
- Pediatric Urinary Antimicrobial Resistance Patterns in a Tertiary Hospital of Northern Greece: A Retrospective Laboratory-Based Surveillance Study.Antibiotics (Basel, Switzerland) · 2026Article
- Antimicrobial Resistance in Pediatric UTIs with Congenital Urogenital Anomalies: An 11-Year Saudi Retrospective Study.Antibiotics (Basel, Switzerland) · 2026Article
- Epidemiologic trends in pediatric urinary tract infections in United States emergency departments from 2016 to 2023.Clinical and experimental emergency medicine · 2026Article
- Discordance between antibiotic therapy and recurrent urinary tract infections in young children with third-generation cephalosporin-resistant infections.Clinical and experimental pediatrics · 2026Article
- Sociodemographic and Clinical Correlates of Multidrug-Resistant Uropathogens in Hospitalized Children.Infection and drug resistance · 2026Article
- Extended-Spectrum β-Lactamase-ProducingAntibiotics (Basel, Switzerland) · 2025Review
- Consequences of host-microbiome interactions in preterm infants.Infection and immunity · 2025Review
- Decoding Proteus mirabilis biofilms: expression of selected virulence genes and association with antibiotic resistance.BMC microbiology · 2025Article
- Trends in Positive Urine Culture Rates and Antimicrobial Resistance in Non-Hospitalized Children from Western Romania: A Retrospective Observational Study.Antibiotics (Basel, Switzerland) · 2025Article
- Comparison of Carbapenem vs. Amikacin Antimicrobial Therapy for Pediatric Acute Pyelonephritis Caused by Extended-Spectrum Β-Lactamase-Positive Enterobacteriaceae.Children (Basel, Switzerland) · 2025Article
- Uropathogens and Their Antimicrobial Resistance Profile at a Pediatric Tertiary Care Hospital in Kathmandu, Nepal.The American journal of tropical medicine and hygiene · 2025Article
- Article
- Evaluating Antibiotic Resistance in Pediatric UTIs: Five-Year Data from a Tertiary Hospital in Turkey.Medicina (Kaunas, Lithuania) · 2025Article
- Influence of meteorological and environmental factors on pediatric urinary tract infections: insights from a 6-year retrospective study in Central China.Frontiers in public health · 2025Article
- Development of a multi-year pediatric antibiogram in Georgia identifies antibiotic resistance changes over the past ten years.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
22 more citing papers are in PubMed but not listed here.
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4 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWe characterize the current national patterns of antibiotic resistance of outpatient pediatric urinary tract infection. MATERIALS AND
methodsWe examined outpatient urinary isolates from patients younger than 18 years in 2009 using The Surveillance Network®, a database with antibiotic susceptibility results and patient demographic data from 195 United States hospitals. We determined the prevalence and antibiotic resistance patterns for the 6 most common uropathogens, ie Escherichia coli, Proteus mirabilis, Klebsiella, Enterobacter, Pseudomonas aeruginosa and Enterococcus. We compared differences in uropathogen prevalence between males and females using chi-square analysis.
resultsWe identified 25,418 outpatient urinary isolates. E. coli was the most common uropathogen overall but the prevalence of E. coli was higher among females (83%) than males (50%, p <0.001). Other common species among males were Enterococcus (17%), P. mirabilis (11%) and Klebsiella (10%). However, these uropathogens each accounted for 5% or less of female isolates (p <0.001). Resistance among E. coli was highest for trimethoprim-sulfamethoxazole (24%) but lower for nitrofurantoin (less than 1%) and cephalothin (15%). Compared to 2002 Surveillance Network data, E. coli resistance rates increased for trimethoprim-sulfamethoxazole (from 23% to 31% in males and from 20% to 23% in females) and ciprofloxacin (from 1% to 10% and from 0.6% to 4%, respectively).
conclusionsE. coli remains the most common pediatric uropathogen. Although widely used, trimethoprim-sulfamethoxazole is a poor empirical choice for pediatric urinary tract infections in many areas due to high resistance rates. First-generation cephalosporins and nitrofurantoin are appropriate narrow-spectrum alternatives given their low resistance rates. Local antibiograms should be used to assist with empirical urinary tract infection treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.