Evidence map›Paper›PMID 23369507›Full record

ArticleGeneral hospital psychiatry

A longitudinal investigation of posttraumatic stress and depressive symptoms over the course of the year following medical-surgical intensive care unit admission.

Dimitry S Davydow, Douglas Zatzick, Catherine L Hough, Wayne J Katon

Registry-linked trialAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02762409 (Improve the Quality of Life After a Hospitalization in Critical Care Thanks to a Program of Prevention of Discomforts Perceived by the Patients of Critical Care Base on Targeted Measures), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02762409 completednot on this map

Improve the Quality of Life After a Hospitalization in Critical Care Thanks to a Program of Prevention of Discomforts Perceived by the Patients of Critical Care Base on Targeted Measures

Typeobservational_patient_registrySponsorCentre Hospitalier of ChartresRan2015 to 2016Enrolled1,006ConditionsDepression, Depression SymptomsArmsexperimental, control
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it, 139 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dimitry S DavydowDepartment of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA 98104, USA. ddavydo1@u.washington.edu
Douglas Zatzick
Catherine L Hough
Wayne J Katon
University of Washington · USBehavioral Tech Research, Inc. · US

Funding

Institute of Translational Health SciencesKL2TR000421 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$12.6M
Psychiatry Primary Care NRSA T-32 AwardT32MH020021 · NIMH · UNIVERSITY OF WASHINGTON · PI JOHN C. FORTNEY, JURGEN UNUTZER · 1998 to 2026
$5.6M
Disseminating Organizational SBI Services (DO-SBIS) at Trauma CentersR01AA016102 · NIAAA · UNIVERSITY OF WASHINGTON · PI ZATZICK, DOUGLAS F · 2007 to 2011
$3.2M
ICU-ACQUIRED NEUROMUSCULAR DYSFUNCTION AND OUTCOMES IN ACUTE LUNG INJURYR01HL096504 · NHLBI · UNIVERSITY OF WASHINGTON · PI HOUGH, CATHERINE LEE, NEEDHAM, DALE MURRAY · 2010 to 2013
$1.5M
Research, Mentoring & Dissemination for PTSD Intervention in Acute Care SettingsK24MH086814 · NIMH · UNIVERSITY OF WASHINGTON · PI ZATZICK, DOUGLAS F · 2010 to 2014
$867k
Substance Abuse and Psychiatric Disorders in Intensive Care Unit SurvivorsR03AA020146 · NIAAA · UNIVERSITY OF WASHINGTON · PI DAVYDOW, DIMITRY SAMUEL · 2010 to 2011
$76k
NCATS NIH HHS KL2 TR000421NCATS NIH HHS KL2 TR000421-12NIAAA NIH HHS R01 AA01602NIAAA NIH HHS R01 AA016102NIAAA NIH HHS R03 AA020146NIAAA NIH HHS R03 AA020146-02NIMH NIH HHS K24 MH086814NIMH NIH HHS K24 MH086814-03NIMH NIH HHS T32 MH020021
6 · The paper itself

Abstract

objectiveThe objective was to identify risk factors for posttraumatic stress disorder (PTSD) and depressive symptoms after medical-surgical intensive care unit (ICU) admission.

methodThis longitudinal investigation included 150 medical-surgical ICU patients. We assessed acute stress and post-ICU PTSD symptoms with the PTSD Checklist-Civilian Version and post-ICU depressive symptoms with the Patient Health Questionnaire-9. Mixed-model linear regression ascertained associations between patient and clinical characteristics and repeated measures of post-ICU PTSD and depressive symptoms.

resultsThe prevalences of substantial PTSD and depressive symptoms were 16% and 31% at 3 months post-ICU and 15% and 17% at 12 months post-ICU, respectively. In-hospital substantial acute stress symptoms [beta: 16.9, 95% confidence Interval (CI): 11.4, 22.4] were independently associated with increased post-ICU PTSD symptoms. Lifetime history of major depression (beta: 2.2, 95% CI: 0.1, 4.2), greater prior trauma exposure (beta: 0.5, 95% CI: 0.2, 0.9) and in-hospital substantial acute stress symptoms (beta: 3.5, 95% CI: 0.8, 6.2) were independently associated with increased post-ICU depressive symptoms.

conclusionsIn-hospital acute stress symptoms may represent a modifiable risk factor for psychiatric morbidity in ICU survivors. Early interventions for at-risk ICU survivors may improve longer-term psychiatric outcomes.

Indexed as

AdultCritical CareDepressionFemaleHumansIntensive Care UnitsLinear ModelsLongitudinal StudiesMaleMiddle AgedOutcome Assessment, Health CareRisk FactorsStress Disorders, Post-TraumaticStress, Psychological

Identifiers

PMID23369507
PMCPMC3644338
OpenAlexW2082100553

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.