ArticleClinical and translational medicine2012
Suboptimal health: a new health dimension for translational medicine.
Article in Clinical and translational medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 111 citations in OpenAlex.
- Effects of mind-body exercise on body constitution and circadian rhythm in people with suboptimal health status.Journal of the Chinese Medical Association : JCMA · 2024Trial
- Discovery, screening and evaluation of a plasma biomarker panel for subjects with psychological suboptimal health state using (1)H-NMR-based metabolomics profiles.Scientific reports · 2016Trial
- Psychosocial, Mental, and Suboptimal Health Measures Are Not Affected by Provision of Abdominal Aortic Calcification Imaging Results: A 12-Week RCT.AJPM focus · 2026Article
- Evaluating the association between job stress and presenteeism among nurses: the mediating role of emotional exhaustion and the moderating effect of leisure crafting.Frontiers in public health · 2026Article
- Online takeaway food consumption and its association with health among young and middle-aged urban residents in mainland China: a cross-sectional study.BMC public health · 2025Article
- A framework for parsing psychopathological heterogeneity: initial application in a large-scale unselected community sample.BMC psychiatry · 2025Article
- Establishment and Evaluation of Fatigue Mice Model in the Convalescence Phase of Influenza A.Viruses · 2025Article
- Analysis of sub-health status and related factors in medical students in the Chinese Mainland from the perspective of health ecology.BMC public health · 2025Article
- "Am I in 'Suboptimal Health'?": The Narratives and Rhetoric in Carving out the Grey Area Between Health and Illness in Everyday Life.Sociology of health & illness · 2025Article
- The association between effort-reward imbalance and job burnout among emergency nurses: the moderating effect of over-commitment.Frontiers in public health · 2025Article
- The prevalence of suboptimal health status among Chinese secondary school students and its relationship with family health: the mediating role of perceived stress and problematic internet use.BMC public health · 2024Article
- Suboptimal health among Chinese middle school students may be associated with psychological symptoms and sleep duration: a cross-sectional survey in China.BMC public health · 2024Article
- Evaluating the association between effort-reward imbalance and suboptimal health status among hospital nurses: a cross-sectional study.International journal of occupational medicine and environmental health · 2024Article
- Article
- Validity and reliability of the Persian version of the Suboptimal Health Status Questionnaire among university staff in Iran.Journal of global health · 2023Article
- Conceptualised psycho-medical footprint for health status outcomes and the potential impacts for early detection and prevention of chronic diseases in the context of 3P medicine.The EPMA journal · 2023Article
- Development and validation of a short-form suboptimal health status questionnaire.The EPMA journal · 2023Article
- Influence of lifestyle on suboptimal health: Insights from a national cross-sectional survey in China.Journal of global health · 2023Article
- Association of IgG N-glycomics with prevalent and incident type 2 diabetes mellitus from the paradigm of predictive, preventive, and personalized medicine standpoint.The EPMA journal · 2023Article
- Psychometric Properties of Suboptimal Health Status Instruments: A Systematic Review.Journal of personalized medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
backgroundOne critical premise of disease-related biomarkers is the definition of the counterpart normality. Contrary to pre-clinical models that can be carefully tailored according to scientific need, heterogeneity and uncontrollability is the essence of humans in health studies. Fully characterization of consistent parameters that define the normal population is the basis to individual differences normalization irrelevant to a given disease process. Self claimed normal status may not represent health because asymptomatic subjects may carry chronic diseases or diseases at their early stage such as cancer, diabetes and hypertension.
methodsThis paper exemplifies the characterization of the suboptimal health status (SHS) which represents a new public health problem in a population with ambiguous health complaints such as general weakness, unexplained medical syndrome and chronic fatigue. We applied clinical informatics approaches and developed a questionnaire for measuring SHS. The validity and reliability of this approach were evaluated in a small pilot study and then in a cross-sectional study of 3,405 individuals.
resultsThe final questionnaire congregated into a score (SHSQ-25) which could significantly distinguish among several abnormal conditions.
conclusionSHSQ-25 could be used as a translational medicine instrument for health measuring in the general population.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.