Evidence map›Paper›PMID 23368953›Full record

SynthesisNutrition journal2013

Micronutrients and pregnancy; effect of supplementation on pregnancy and pregnancy outcomes: a systematic review.

Taddese Alemu Zerfu, Henok Taddese Ayele

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrition journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Functional status of women with and without potentially life-threatening maternal conditions after 6 months postpartum: A cohort study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  15. Determinants of adverse birth outcomes among women delivered in public hospitals of Ethiopia, 2020.Archives of public health = Archives belges de sante publique · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Taddese Alemu ZerfuCollege of Health Sciences and Referral Hospital, Dilla University, Dilla, Ethiopia. tadal2006@yahoo.com
Henok Taddese Ayele
Dilla University · ETUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEvery year more than 20 million infants are born with low birth weight worldwide. About 3.6 million infants die during the neonatal period. More than one third of child deaths are thought to be attributable to maternal and child under nutrition.

objectivesTo systematically review the effect of supplementing various combinations and types of micronutrients on the course and outcomes of pregnancy.

methodsElectronic search of Medline, Pub Med, Health Internetwork access to Research Initiative, and Google Scholar databases was conducted. Outcomes of interest were birth weight, low birth weight, small size for gestational age, prenatal mortality and neonatal mortality. After exclusion of irrelevant /incomplete ones, 17 out of 115 articles were considered for the final analysis.

findingsMajority of the articles reviewed favored the supplementation of micronutrients to pregnant mother. Some studies suggested calcium supplementation is associated with a significant protective benefit in the prevention of pre-eclampsia. The remaining articles reviewed, showed significant benefit of Multiple Micronutrients supplementation during pregnancy in reducing low birth weight, small for Gestational Age births as compared to the usual iron-folate supplements.

conclusionsSupplying micronutrients, mainly multiple micronutrients have beneficial effect in reducing the risk of low birth weight and other complications. Further studies at various combination and doses of micronutrient supplements are recommended.

Indexed as

Dietary SupplementsPregnancy OutcomeBirth WeightCalcium, DietaryFemaleFolic AcidGestational AgeHumansInfant, Low Birth WeightInfant MortalityInfant, NewbornIron, DietaryMicronutrientsPre-EclampsiaPregnancyRandomized Controlled Trials as TopicCalcium, DietaryFolic AcidIron, DietaryMicronutrients

Identifiers

PMID23368953
PMCPMC3585818
OpenAlexW2144234247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.