Evidence map›Paper›PMID 23367970›Full record

ArticlePhysical review. E, Statistical, nonlinear, and soft matter physics2012

Cell elongation via intrinsic antipodal stretching forces.

T Sawetzki, C D Eggleton, D W M Marr

Abstract read
In one paragraph

Article in Physical review. E, Statistical, nonlinear, and soft matter physics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. High-throughput linear optical stretcher for mechanical characterization of blood cells.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2016
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

T SawetzkiChemical and Biological Engineering Department, Colorado School of Mines, Golden, Colorado 80401, USA.
C D Eggleton
D W M Marr

Funding

High-Throughput Cell Mechanical Property Testing for Label-Free AssayingR01AI079347 · NIAID · COLORADO SCHOOL OF MINES · PI EGGLETON, CHARLES DIONISIO, MARR, DAVID WM · 2009 to 2012
$1.3M
NIAID NIH HHS 1R01 AI079347NIAID NIH HHS R01 AI079347
6 · The paper itself

Abstract

To probe the mechanical properties of cells, we investigate a technique to perform deformability-based cytometry that inherently induces normal antipodal surface forces using a single line-shaped optical trap. We show theoretically that these opposing forces are generated simultaneously over curved microscopic object surfaces with optimal magnitude at low numerical apertures, allowing the directed stretching of elastic cells with a single, weakly focused laser source. Matching these findings with concomitant experimental observations, we elongate red blood cells, effectively stretching them within the narrow confines of a steep, optically induced potential well.

Indexed as

Cell ShapeAnisotropyBiophysicsColloidsElasticityErythrocyte DeformabilityErythrocyte MembraneErythrocytesFlow CytometryHumansLasersModels, StatisticalOptical TweezersStress, MechanicalColloids

Identifiers

PMID23367970
PMCPMC3566237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.