Evidence map›Paper›PMID 23367115›Full record

ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2012

Recursive feature elimination for brain tumor classification using desorption electrospray ionization mass spectrometry imaging.

Behnood Gholami, Isaiah Norton, Allen R Tannenbaum, Nathalie Y R Agar

Abstract read
In one paragraph

Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Emerging Computational Methods in Mass Spectrometry Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  5. Advances in Intraoperative Flow Cytometry.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Behnood GholamiDepartment of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA. bgholami@bwh.harvard.edu
Isaiah Norton
Allen R Tannenbaum
Nathalie Y R Agar

Funding

Washington University ConsoritumU54EB005149 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI VAN HORN, JOHN · 2004 to 2013
$39.3M
WHITE MATTER ARCHITECTURE FROM DT-MRIP41RR013218 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON · 1998 to 2011
$30.6M
Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI PUJOL, SONIA · 2012 to 2022
$20.9M
Image Guided Therapy Center - Ultrasound-based sensor system for the monitoring of COVID-19 patientsP41EB015898 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI TEMPANY, CLARE M · 2012 to 2021
$18.9M
IMAGE GUIDED THERAPY CENTERP41RR019703 · NCRR · BRIGHAM AND WOMEN'S HOSPITAL · PI JOLESZ, FERENC A · 2010 to 2011
$8.6M
Real-Time Stereotactic Mass Spectrometry Tissue Analysis for Intraoperative NeuroDP2OD007383 · OD · BRIGHAM AND WOMEN'S HOSPITAL · PI AGAR, NATHALIE YR · 2010 to 2010
$2.7M
NCRR NIH HHS P41 RR013218NCRR NIH HHS P41-RR-013218NCRR NIH HHS P41 RR019703NIBIB NIH HHS P41 EB015898NIBIB NIH HHS P41 EB015902NIBIB NIH HHS P41-EB-015902NIBIB NIH HHS U54 EB005149NIH HHS DP2 OD007383
6 · The paper itself

Abstract

The metabolism and composition of lipids is of increasing interest for understanding and detecting disease processes. Lipid signatures of tumor type and grade have been demonstrated using magnetic resonance spectroscopy. Clinical management and ultimate prognosis of brain tumors depend largely on the tumor type, subtype, and grade. Mass spectrometry, a well-known analytical technique used to identify molecules in a given sample based on their mass, can significantly improve the problem of tumor type classification. This work focuses on the problem of identifying lipid features to use as input for classification. Feature selection could result in improvements in classifier performance, discovery of biomarkers, improved data interpretation, and patient treatment.

Indexed as

AlgorithmsBiomarkers, TumorBrain NeoplasmsDiagnosis, Computer-AssistedGliomaHumansReproducibility of ResultsSensitivity and SpecificitySpectrometry, Mass, Electrospray IonizationBiomarkers, Tumor

Identifiers

PMID23367115
PMCPMC3649005

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.