Evidence map›Paper›PMID 23366741›Full record

Trial reportAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2012

Volumetric detection of colorectal lesions for noncathartic dual-energy computed tomographic colonography.

Janne J Näppi, Se Hyung Kim, Hiroyuki Yoshida

Abstract readClinical Trial
In one paragraph

Trial report in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Context-specific method for detection of soft-tissue lesions in non-cathartic low-dose dual-energy CT colonography.Proceedings of SPIE--the International Society for Optical Engineering · 2015
    Article
  2. Information-Preserving Pseudo-Enhancement Correction for Non-Cathartic Low-Dose Dual-Energy CT Colonography.Abdominal imaging : computational and clinical applications : 6th International Workshop, ABDI 2014, held in conjunction with MICCAI 2014, Cambridge, MA, USA, September 14, 2014. ABDI (Workshop) (6th : 2014 : Cambridge, Mass.) · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Janne J NäppiDepartment of Radiology of Harvard Medical School, 25 New Chardon Street, Suite 400C, Boston, MA 02114, USA. jnappi@partners.org
Se Hyung Kim
Hiroyuki Yoshida

Funding

Computerized Detection of Polyps in CT ColonographyR01CA095279 · NCI · UNIVERSITY OF CHICAGO · PI YOSHIDA, HIROYUKI · 2003 to 2013
$3.3M
NA-MIC virtual colonoscopyR01CA131718 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI YOSHIDA, HIROYUKI · 2009 to 2012
$2.1M
In Vivo Detection of Flat Colorectal Neoplasms with CT ColonographyR21CA140934 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI NAPPI, JANNE JOHANNES · 2009 to 2010
$428k
Computerized Detection of Polyps in CT ColonographyR56CA095279 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI YOSHIDA, HIROYUKI · 2009 to 2009
$384k
Diagnosis of non-polypoid neoplasia of the colon with CT colonographyR03CA139600 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI YOSHIDA, HIROYUKI · 2009 to 2010
$177k
NCI NIH HHS CA095279NCI NIH HHS CA131718NCI NIH HHS CA139600NCI NIH HHS CA140934NCI NIH HHS R01 CA095279NCI NIH HHS R01 CA131718NCI NIH HHS R03 CA139600NCI NIH HHS R21 CA140934NCI NIH HHS R56 CA095279
6 · The paper itself

Abstract

Noncathartic computed tomographic colonography (CTC) could significantly increase patient adherence to colorectal screening guidelines. However, radiologists find the interpretation of noncathartic CTC images challenging. We developed a fully automated computer-aided detection (CAD) scheme for assisting radiologists with noncathartic CTC. A volumetric method is used to detect lesions within a thick target region encompassing the colonic wall. Dual-energy CTC (DE-CTC) is used to provide more detailed information about the colon than what is possible with conventional CTC. False-positive detections are reduced by use of a random-forest classifier. The effect of the thickness of the target region on detection performance was assessed by use of 22 clinical noncathartic DE-CTC studies including 27 lesions ≥6 mm. The results indicate that the thickness parameter can have significant effect on detection accuracy. Leave-one-patient-out evaluation indicated that the proposed CAD scheme detects colorectal lesions at high accuracy in noncathartic CTC.

Indexed as

CatharticsColonColonography, Computed TomographicColorectal NeoplasmsCone-Beam Computed TomographyFalse Positive ReactionsHumansRadiography, AbdominalCathartics

Identifiers

PMID23366741
PMCPMC3969820

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.